Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Prompt recognition of microbes by cells is critical to eliminate invading pathogens. Some cell-
associated pattern recognition receptors (PRRs) recognize and respond to microbial …

In response to danger signals, macrophages rapidly produce many inflammatory cytokines
that trigger the cascade release of inflammatory mediators, leading to tissue damage, which …

Brucella spp. are facultatively intracellular bacteria that can infect, survive, and multiply in
various host cell types in vivo and/or in vitro. The genus Brucella has markedly expanded in …

Research on Brucella pathogenesis has focused primarily on its ability to cause persistent
intracellular infection of the mononuclear phagocyte system. At these sites, Brucella abortus …

Brucella is a facultative intracellular pathogen that preferentially colonizes reproductive
organs and utilizes erythritol as a preferred carbon source for its survival and proliferation. In …

Osteoarticular disease is a frequent complication of human brucellosis. Vaccination remains
a critical component of brucellosis control, but there are currently no vaccines for use in …

Reproductive failure is the hallmark of brucellosis in animals. An uncommon but important
complication in pregnant women who become acutely infected with Brucella melitensis is …

Brucella is an intracellular pathogen which has developed some mechanisms to face the
adversities found inside the host. Among all the mechanisms of Brucella, we centered our …