The role of hepatokines in NAFLD

N Stefan, F Schick, AL Birkenfeld, HU Häring, MF White - Cell metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

Androgen dysfunction in non-alcoholic fatty liver disease: Role of sex hormone binding globulin

MJ Song, JY Choi - Frontiers in Endocrinology, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
in the world. It is linked mainly to insulin resistance and metabolic syndrome including …

The impact of Vitamin D and L-Cysteine co-supplementation on upregulating glutathione and Vitamin D-metabolizing genes and in the treatment of circulating 25 …

SK Jain, J Justin Margret, SA Abrams, SN Levine… - Nutrients, 2024 - mdpi.com
Vitamin D receptors are expressed in many organs and tissues, which suggests that vitamin
D (VD) affects physiological functions beyond its role in maintaining bone health. Deficiency …

The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk …

A Lonardo - Expert Review of Clinical Pharmacology, 2023 - Taylor & Francis
ABSTRACT Introduction Metabolic syndrome (MetS), ie the cluster of cardiometabolic risk
factors comprising visceral obesity, impaired glucose metabolism, arterial hypertension and …

Sex hormone-binding globulin improves lipid metabolism and reduces inflammation in subcutaneous adipose tissue of metabolic syndrome-affected horses

L Bourebaba, M Kępska, B Qasem, M Zyzak… - Frontiers in molecular …, 2023 - frontiersin.org
Equine metabolic syndrome (EMS) is a steadily growing endocrine disorder representing a
real challenge in veterinary practice. As a multifactorial condition, EMS is characterized by …

Alternative dosing regimen of exemestane in a randomized presurgical trial: the role of obesity in biomarker modulation

H Johansson, A Guerrieri-Gonzaga, S Gandini… - NPJ Breast …, 2024 - nature.com
In a 3-arm presurgical trial, four-six weeks exemestane 25 mg three times/week (TIW) was
non-inferior to 25 mg/day (QD) in suppressing circulating estradiol in postmenopausal …

Causal relationship between sex hormone‐binding globulin and major depression: A Mendelian randomization study

H Zhu, Y Sun, S Guo, Q Zhou, Y Jiang… - Acta Psychiatrica …, 2023 - Wiley Online Library
Objective This study aimed to explore the causal relationship between sex hormone‐binding
globulin (SHBG) and major depression using two‐sample Mendelian randomization (MR) …

Effects of vitamin D and L-cysteine cosupplementation on circulating bioavailable and total 25-hydroxy-vitamin D, the free/total testosterone ratio and inflammatory …

SK Jain, JJ Margret, A Zachary, MM Lally… - … , Prevention & Health, 2024 - nutrition.bmj.com
Background Subjects with metabolic syndrome and obesity have higher levels of
inflammation with depression of the vitamin D (VD) hydroxylase/metabolising genes …

Targeting metabolic pathways: a novel therapeutic direction for type 2 diabetes

Z Song, A Yan, Z Guo, Y Zhang, T Wen, Z Li… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease that causes
multi-organ complications, seriously affecting patients' quality of life and survival …

[HTML][HTML] Pathogenesis and research progress of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

GY Shan, H Wan, YX Zhang, JY Cheng… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
In this editorial, we comment on the article by Mei et al. Nonalcoholic steatohepatitis (NASH)
is a severe inflammatory subtype of nonalcoholic fatty liver disease (NAFLD) with …