A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts

MJ Ward, SA Ellsworth, GS Nystrom - Toxicon, 2018 - Elsevier
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …

Scorpion venomics: a 2019 overview

JI Cid-Uribe, JI Veytia-Bucheli… - Expert review of …, 2020 - Taylor & Francis
Introduction: A few scorpions are dangerous to humans. Their medical relevance was the
initial driving force for venom research. By classical biochemistry and molecular cloning …

Identification, classification, and characterization of alpha and beta subunits of LVP1 protein from the venom gland of four Iranian scorpion species

F Salabi, B Vazirianzadeh, M Baradaran - Scientific Reports, 2023 - nature.com
Scorpion venoms contain bioactive peptides and proteins. Some, can be used for
pharmaceutical purposes. So, identification of venom proteins matters because, in addition …

Evaluating the performance of de novo assembly methods for venom-gland transcriptomics

ML Holding, MJ Margres, AJ Mason, CL Parkinson… - Toxins, 2018 - mdpi.com
Venom-gland transcriptomics is a key tool in the study of the evolution, ecology, function,
and pharmacology of animal venoms. In particular, gene-expression variation and coding …

Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions

UC de Oliveira, MY Nishiyama Jr, MBV Dos Santos… - PloS one, 2018 - journals.plos.org
Background Except for the northern region, where the Amazonian black scorpion, T.
obscurus, represents the predominant and most medically relevant scorpion species, Tityus …

The enzymatic core of scorpion venoms

G Delgado-Prudencio, JI Cid-Uribe, JA Morales… - Toxins, 2022 - mdpi.com
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a
primary role in envenomation, in scorpions, their function appears to be ancillary in most …

Venom-gland transcriptomics and venom proteomics of the Hentz striped scorpion (Centruroides hentzi; Buthidae) reveal high toxin diversity in a harmless member of …

MJ Ward, SA Ellsworth, DR Rokyta - Toxicon, 2018 - Elsevier
Of the 14 extant scorpion families, Buthidae has the most thoroughly characterized venoms.
Most of this characterization, however, has been limited to species with medically significant …

The Dual Prey-Inactivation Strategy of Spiders—In-Depth Venomic Analysis of Cupiennius salei

L Kuhn-Nentwig, N Langenegger, M Heller, D Koua… - Toxins, 2019 - mdpi.com
Most knowledge of spider venom concerns neurotoxins acting on ion channels, whereas
proteins and their significance for the envenomation process are neglected. The here …

Phylogenomics facilitates stable scorpion systematics: reassessing the relationships of Vaejovidae and a new higher-level classification of Scorpiones (Arachnida)

CE Santibáñez-López, E González-Santillán… - Molecular Phylogenetics …, 2019 - Elsevier
Abstract The Neartic family Vaejovidae (Scorpiones: Chactoidea) has long been treated as a
diverse and systematically cohesive group of scorpions, but its monophyly and relationship …

MS/MS analysis of four scorpion venoms from Colombia: a descriptive approach

S Estrada-Gómez, LJ Vargas-Muñoz… - Journal of Venomous …, 2021 - SciELO Brasil
Background: Scorpions are widely known for the neurotoxic effects of their venoms, which
contain peptides affecting ionic channels. Although Colombia is recognized for its scorpion …