Malaysia's breakthrough in Modern Actinobacteria (MOD-ACTINO) drug discovery research

AYK Thye, V Letchumanan, LTH Tan… - … in Microbes and …, 2022 - research.monash.edu
Actinobacteria are well-known producers of metabolites with medicinal value. The
application of actinobacterial compounds has been expanded to other fields, including …

Biocontrol of Cercospora leaf spot disease and enhancement of defense response in Vigna radiata (L.) R. Wilczek (Mung Bean) plants using bioformulation of …

DS Basavarajappa, RS Kumar, MP Bhat… - … Agricultural Science & …, 2023 - ACS Publications
Enhancement of disease resistance using beneficial microbes is one of the promising and
eco-friendly strategies for disease management in crop plants. The talcum formulation of …

Interactions of Different Streptomyces Species and Myxococcus xanthus Affect Myxococcus Development and Induce the Production of DK-Xanthenes

RI Santamaría, A Martínez-Carrasco, JR Tormo… - International Journal of …, 2023 - mdpi.com
The co-culturing of microorganisms is a well-known strategy to study microbial interactions
in the laboratory. This approach facilitates the identification of new signals and molecules …

Metabolic perturbation of Streptomyces albulus by introducing NADP-dependent glyceraldehyde 3-phosphate dehydrogenase

J Mao, M Zhang, W Dai, C Fu, Z Wang… - Frontiers in …, 2024 - frontiersin.org
The available resources of Streptomyces represent a valuable repository of bioactive natural
products that warrant exploration. Streptomyces albulus is primarily utilized in the industrial …

LC-MS Chemical Profiling, In Silico Docking Studies to Unravel the Therapeutic Potential of Streptomyces hygroscopicus as a Source of Antimalarial Bioactive …

AA Farahdina, SA Ardiyanti… - Tropical Journal of …, 2024 - search.ebscohost.com
Malaria is a disease transmitted through the bite of female Anopheles mosquitoes carrying
Plasmodium parasite. The resistance of the Plasmodium parasite against antimalarial drugs …

[HTML][HTML] Dataset of the complete genome of Streptomyces cavourensis strain 2BA6PGT isolated from sediment from the bottom of the salt lake Verkhnee Beloe …

ETJ Chong, KK Png, E Abidueva, S Zaitseva, C Sun… - Data in Brief, 2023 - Elsevier
The Streptomyces cavourensis strain 2BA6PG T was isolated from sediment from the bottom
of the salt lake Verkhnee Beloe (Buryatia, Russia). This strain's 7,651,223 bp complete …

Antibacterial Activities of Secondary Metabolites Derived from Streptomyces sp. VITGV38 (MCC4869) against Selected Uropathogens.

A Hussain… - Journal of Pure & Applied …, 2023 - search.ebscohost.com
Abstract Streptomyces sp. VITGV38 (MCC8469) was obtained from the VIT University
Microbiology Laboratory where it was isolated from tomato plants. This strain was mass …

Active compound profiling in fraction 49 of a secondary metabolite extract from Streptomyces hygroscopicus subsp. Hygroscopicus as antimalaria drug using LCMS …

SA Ardiyanti, AA Farahdina, LE Fitri, N Widodo - 2024 - researchsquare.com
Background Antimalarial resistance in Indonesia is caused by mutations at the drug target
sites and biochemical changes in drug receptors. Previous research indicates that only …

GSK-3β inhibition with antiplasmodial activities from the extracts of actinomycetes isolated from Malaysian forest soil.

F Mahmud, AH Ali, AFA Aziz, D Nur… - Malaysian Journal …, 2023 - search.ebscohost.com
Abstract Aims: Glycogen synthase kinase-3 (GSK-3 (EC: 2.7. 11.1)) is one of the main
therapeutic targets for treating cancer, diabetes, neurological illness and parasitic infection …

Investigation of Anti-dengue Virus (DeNV) Molecules from a Marine-Derived Bacterium

P Ahmadi, T Haruyama, N Kobayashi… - Proceedings of the 1st …, 2023 - books.google.com
Dengue is a viral infection spread by mosquitos that occur in tropical and subtropical areas
in the world. Presently, there is no directly acting drug against Dengue Virus (DeNV) for …