[HTML][HTML] TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease

MP Fautsch, ED Wieben, KH Baratz… - Progress in retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in
the elderly. Since the first description of an association between FECD and common …

Transcription factor 4 and its association with psychiatric disorders

JR Teixeira, RA Szeto, VMA Carvalho… - Translational …, 2021 - nature.com
The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription
factor widely expressed throughout the body and during neural development. Mutations in …

[HTML][HTML] Immunosuppressive CD10+ ALPL+ neutrophils promote resistance to anti-PD-1 therapy in HCC by mediating irreversible exhaustion of T cells

Y Meng, F Ye, P Nie, Q Zhao, L An, W Wang, S Qu… - Journal of …, 2023 - Elsevier
Background & Aims Remodeling the tumor microenvironment is a critical strategy for treating
advanced hepatocellular carcinoma (HCC). Yet, how distinct cell populations in the …

Trihelix Transcriptional Factor GhGT26 of Cotton Enhances Salinity Tolerance in Arabidopsis

Y Li, Z Hu, Y Dong, Z Xie - Plants, 2022 - mdpi.com
Cotton (Gossypium hirsutum L.), the most important textile crop worldwide, often encounters
abiotic stress during its growing season and its productivity is significantly limited by adverse …

Functional consequences of TCF4 missense substitutions associated with Pitt-Hopkins syndrome, mild intellectual disability, and schizophrenia

A Sirp, K Roots, K Nurm, J Tuvikene, M Sepp… - Journal of Biological …, 2021 - ASBMB
Transcription factor 4 (TCF4) is a basic helix-loop-helix transcription factor essential for
neurocognitive development. The aberrations in TCF4 are associated with …

MESP2 binds competitively to TCF4 to suppress gastric cancer progression by regulating the SKP2/p27 axis

L Ge, G Zhao, C Lan, H Song, D Qi, P Huang, X Ke… - Cell death …, 2023 - nature.com
Gastric cancer (GC) is a major cause of human deaths worldwide, and is notorious for its
high incidence and mortality rates. Mesoderm Posterior Basic Helix-loop-helix (bHLH) …

[图书][B] TCF4 Is a Key Mediator of Cell Identity and Oncogenesis in Neuroblastoma

N Aljouda - 2023 - search.proquest.com
Neuroblastomas (NB) are embryonal childhood tumors that derive from the multipotent
neural crest cells (NCCs) of the peripheral nervous system. NB accounts for more than 15 …

Elucidating the Effects of ERα: Isoform Expression and Differential Receptor Localization in Immune Function

C Leyers - 2022 - medica-musc.researchcommons.org
Estrogen can be anti-or pro-inflammatory depending on milieu and has a role in increased
incidence of lupus in reproductive age women versus men. Estrogen's pleiotropic effects are …

The Effect of 8 Weeks of High Intensity Training vs High Volume Training on TCF4/CHOP10 Gene Complexes of Subcutaneous Fat Tissue in Male Rats

M Khoshbin, S Naghibi… - Jundishapur Scientific …, 2022 - jsmj.ajums.ac.ir
Background and Objectives This study aims to evaluate the effect of different intensities of
aerobic trainingon the expression of transcription factor 4 (TCF4) and C/EBP homologous …

[PDF][PDF] تأثیر 8 هفته تمرینات شدید در مقابل تمرینات با حجم بالا بر کمپلکس ژنی فاکتور رونویسی 4/پروتئین همولوگ C/EBP-10 بافت چربی زیرجلدی رتهای نر.

ملیکا خوشبین, سعید نقیبی… - Jundishapur Scientific …, 2022‎ - jsmj.ajums.ac.ir
Results There was a significant difference in the expression of CHOP10 gene in the
subcutaneous tissue of male Wistar rats in the HIIT group compared to the MIT and control …