Efficient saccharification of lignocellulosic biomass requires concerted development of a
pretreatment method, an enzyme cocktail and an enzymatic process, all of which are …

Biomass constitutes an appealing alternative to fossil resources for the production of
materials and energy. The abundance and attractiveness of vegetal biomass come along …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …

Lytic polysaccharide monooxygenases (LPMOs) are powerful monocopper enzymes that
can activate strong C–H bonds through a mechanism that remains largely unknown. Herein …

The discovery of lytic polysaccharide monooxygenases (LPMOs) has revolutionized
enzymatic processing of polysaccharides, in particular, recalcitrant insoluble …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Natural carbohydrate polymers such as starch, cellulose, and chitin provide renewable
alternatives to fossil fuels as a source for fuels and materials. As such, there is considerable …

A structural unit found in the active site of some copper proteins, the histidine brace, is
comprised of an N-terminal histidine that chelates a single copper ion through its amino …

Highlights•Lytic polysaccharide monooxygenases (LPMOs) are abundant in nature and of
great biotechnological interest.•Substrate binding affects the catalytic competence of the …

Enzymatic conversion of polysaccharides into lower-molecular-weight, soluble
oligosaccharides is dependent on the action of hydrolytic and oxidative enzymes …