Pore-forming toxins (PFTs) are widely distributed in both Gram-negative and Gram-positive
bacteria. PFTs can act as virulence factors that bacteria utilise in dissemination and host …

Pore-forming toxins (PFTs) are important virulence factors produced by many pathogenic
bacteria. Here, we show that the Vibrio cholerae toxin MakA is a novel cholesterol-binding …

Understanding the interactions between drugs and enzymes is crucial for designing effective
therapeutics. This study employed a combination of molecular docking and molecular …

The protein MakA was discovered as a motility-associated secreted toxin from Vibrio
cholerae. Here, we show that MakA is part of a gene cluster encoding four additional …

Pathogenic serotypes of Vibrio cholerae, transmitted through contaminated water and food,
are responsible for outbreaks of cholera, an acute diarrheal disease. While the cholera toxin …

Alpha-pore-forming toxins (α-PFTs) are secreted by many species of bacteria, including
Escherichia coli, Aeromonas hydrophila, and Bacillus thuringiensis, as part of their arsenal …

The α-pore-forming toxins (α-PFTs) from pathogenic bacteria damage host cell membranes
by pore formation. We demonstrate a remarkable, hitherto unknown mechanism by an α-PFT …

Bacteria produce different virulence factors through which they are capable of cells or
tissues of the organism they infect. Among the virulence factors production of capsules …