Alternative tumour-specific antigens

CC Smith, SR Selitsky, S Chai, PM Armistead… - Nature Reviews …, 2019 - nature.com
The study of tumour-specific antigens (TSAs) as targets for antitumour therapies has
accelerated within the past decade. The most commonly studied class of TSAs are those …

Initial diagnostic workup of acute leukemia: guideline from the College of American Pathologists and the American Society of Hematology

DA Arber, MJ Borowitz, M Cessna… - … of pathology & …, 2017 - meridian.allenpress.com
Context.—A complete diagnosis of acute leukemia requires knowledge of clinical
information combined with morphologic evaluation, immunophenotyping and karyotype …

The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia

C Owen, J Fitzgibbon, P Paschka - Hematological oncology, 2010 - Wiley Online Library
Recurrent genetic aberrations are important predictors of outcome in acute myeloid
leukaemia (AML). Numerous novel molecular abnormalities have been identified and …

Wilms' tumor gene 1 expression: an independent acute leukemia prognostic indicator following allogeneic hematopoietic SCT

XS Zhao, S Jin, HH Zhu, LP Xu, DH Liu… - Bone marrow …, 2012 - nature.com
To evaluate the prognostic significance of Wilms' tumor gene 1 (WT1) expression for
monitoring minimal residual disease and predicting relapse in patients with acute leukemia …

Combined use of WT1 and flow cytometry monitoring can promote sensitivity of predicting relapse after allogeneic HSCT without affecting specificity

X Zhao, C Yan, D Liu, L Xu, Y Liu, K Liu, Y Qin… - Annals of …, 2013 - Springer
Either WT1 or leukemia-associated aberrant immune phenotypes (LAIPs) was one of the
minimal residual disease (MRD) parameters used to predict leukemia relapse after …

Clinical significance of minimal residual disease detected by multidimensional flow cytometry: serial monitoring after allogeneic stem cell transplantation for acute …

T Miyazaki, H Fujita, K Fujimaki, T Hosoyama… - Leukemia research, 2012 - Elsevier
We analyzed minimal residual disease (MRD) by multidimensional flow cytometry (MFC)
after allogeneic stem cell transplantation in 41 patients with acute myeloid leukemia …

Biological activities of extracts and compounds from Thai Kae-Lae (Maclura cochinchinensis (Lour.) Corner)

L Rueankham, P Panyajai, A Saiai… - … Medicine and Therapies, 2023 - Springer
Background and aims The purpose of this study was to investigate the biological properties
of Kae-Lae (Maclura cochinchinensis (Lour.) Corner), a traditional medicinal plant used in …

Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia

Y He, Z Liang, M Wu, Q Wen, L Deng, C Song, B Wu… - Leukemia research, 2015 - Elsevier
Molecular markers have become an invaluable tool in monitoring disease status particularly
of leukemias, as bone marrow samples can be easily collected for analysis during all stages …

Prognostic significance of WT1 expression at diagnosis and end of induction in Egyptian adult acute myeloid leukemia patients

GI Mossallam, TM Abdel Hamid, HK Mahmoud - Hematology, 2013 - Taylor & Francis
Abstract Background Wilms' tumor (WT1) gene overexpression has been reported in the
majority of acute myeloid leukemia (AML) patients at diagnosis and has been evaluated as …

WT1 overexpression affecting clinical outcome in non-hodgkin lymphomas and adult acute lymphoblastic leukemia

Z Ujj, G Buglyó, M Udvardy, G Vargha, S Biró… - Pathology & Oncology …, 2014 - Springer
Abstract The Wilms tumor 1 (WT1) gene has a complex role as a transcriptional regulator,
acting as tumor suppressor or oncogene in different malignancies. The prognostic role of its …