Recent progress in the analysis of transcriptional regulation has revealed the presence of an
exquisite functional network comprising the Maf and Cap'n'collar (CNC) families of …

Segmentation is an important process that is frequently used during development to
segregate groups of cells with distinct features. Segmental compartments provide a …

Ets is a family of transcription factors present in species ranging from sponges to human. All
family members contain an approximately 85 amino acid DNA binding domain, designated …

Analyses in mouse models have revealed crucial roles for MafA (musculoaponeurotic
fibrosarcoma oncogene family A) and MafB in islet β cells, with MafB being required during …

Of the three critical enhancer elements that mediate β-cell-specific and glucose-responsive
expression of the insulin gene, only the identity of the transcription factor binding to the …

Vertebrate innovations include neural crest cells and their derivatives, neurogenic placodes,
an elaborate segmented brain, endoskeleton, and an increase in the number of genes in the …

Understanding the patterning mechanisms that control head development—particularly the
neural crest and its contribution to bones, nerves and connective tissue—is an important …

The inner ear is a complex sensory organ responsible for balance and sound detection in
vertebrates. It originates from a transient embryonic structure, the otic vesicle, that contains …

Diethylstilbestrol (DES) was widely used to treat pregnant women through 1971. The
reproductive tracts of their female offspring exposed to DES in utero are characterized by …

Most animals exhibit distinctive and diverse morphological features on their anterior‐
posterior body axis. However, underneath the variation in design and developmental …