[HTML][HTML] Saliva-based microfluidic point-of-care diagnostic

TW Pittman, DB Decsi, C Punyadeera, CS Henry - Theranostics, 2023 - ncbi.nlm.nih.gov
There has been a long-standing interest in point-of-care (POC) diagnostics as a tool to
improve patient care because it can provide rapid, actionable results near the patient. Some …

[HTML][HTML] Understanding human health through metatranscriptomics

T Ojala, E Kankuri, M Kankainen - Trends in Molecular Medicine, 2023 - cell.com
Metatranscriptomics has revolutionized our ability to explore and understand transcriptional
programs in microbial communities. Moreover, it has enabled us to gain deeper and more …

Data-centric artificial intelligence in oncology: a systematic review assessing data quality in machine learning models for head and neck cancer

J Adeoye, L Hui, YX Su - Journal of Big Data, 2023 - Springer
Abstract Machine learning models have been increasingly considered to model head and
neck cancer outcomes for improved screening, diagnosis, treatment, and prognostication of …

Noncoding RNAs in oral cancer

J Balakittnen, CE Weeramange… - Wiley …, 2023 - Wiley Online Library
Oral cancer (OC) is the most prevalent subtype of cancer arising in the head and neck
region. OC risk is mainly attributed to behavioral risk factors such as exposure to tobacco …

The hitchhikers' guide to RNA sequencing and functional analysis

JW Chen, L Shrestha, G Green, A Leier… - Briefings in …, 2023 - academic.oup.com
DNA and RNA sequencing technologies have revolutionized biology and biomedical
sciences, sequencing full genomes and transcriptomes at very high speeds and reasonably …

Artificial intelligence in salivary biomarker discovery and validation for oral diseases

J Adeoye, YX Su - Oral Diseases, 2024 - Wiley Online Library
Salivary biomarkers can improve the efficacy, efficiency, and timeliness of oral and
maxillofacial disease diagnosis and monitoring. Oral and maxillofacial conditions in which …

Microbiomes, their function, and cancer: how metatranscriptomics can close the knowledge gap

L Aitmanaitė, K Širmonaitis, G Russo - International journal of molecular …, 2023 - mdpi.com
The interaction between the microbial communities in the human body and the onset and
progression of cancer has not been investigated until recently. The vast majority of the …

Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy

M Constantin, MC Chifiriuc, G Mihaescu… - Frontiers in …, 2023 - frontiersin.org
Head and neck cancer (HNC) is the sixth most common type of cancer, with more than half a
million new cases annually. This review focuses on the role of oral dysbiosis and HPV …

Machine learning-based genome-wide salivary DNA methylation analysis for identification of noninvasive biomarkers in oral cancer diagnosis

J Adeoye, CCJ Wan, LW Zheng, P Thomson, SW Choi… - Cancers, 2022 - mdpi.com
Simple Summary Because tissue biopsy is the gold standard for diagnosing oral cancer, it is
often performed to confirm disease during screening, management, and monitoring …

Detecting salivary host and microbiome RNA signature for aiding diagnosis of oral and throat cancer

G Banavar, O Ogundijo, C Julian, R Toma, F Camacho… - Oral Oncology, 2023 - Elsevier
Objective Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell
carcinoma (OPSCC) can go undetected resulting in late detection and poor outcomes. We …