Overcoming multiple drug resistance in lung cancer using siRNA targeted therapy

S Naghizadeh, A Mohammadi, B Baradaran… - Gene, 2019 - Elsevier
Among cancers, lung cancer is the most morbidity and mortality disease that is remaining
the fatalist. Generally, there are multiple treatment procedures for lung cancer, such as …

Surface engineered dendrimers in siRNA delivery and gene silencing

V Tambe, S Thakkar, N Raval, D Sharma… - Current …, 2017 - ingentaconnect.com
Background: Therapeutic efficacy of dreadful diseases like cancer, HIV (Human
Immunodeficiency Virus) can be enhanced by delivering molecules which regulate function …

Gene silencing strategies in cancer therapy: an update for drug resistance

S Naghizadeh, B Mansoori… - Current medicinal …, 2019 - ingentaconnect.com
RNAi, post-transcriptional gene silencing mechanism, could be considered as one of the
most important breakthroughs and rapidly growing fields in science. Researchers are trying …

Assessment of biofilm formation in Pseudomonas aeruginosa by antisense mazE-PNA

H Valadbeigi, N Sadeghifard, MB Salehi - Microbial pathogenesis, 2017 - Elsevier
The hallmark patogenicity in Pseudomonas aeruginosa (P. aeruginosa) is biofilm formation
that is not easy to eradicate, because it has variety mechanisms for antibiotic resistance. In …

SiRNA mediated gene silencing: Hurdles, strategies and applications

P Tambe, P Kumar, V Gajbhiye… - Pharmaceutical …, 2015 - ingentaconnect.com
Background: RNA interference (RNAi) has emerged as one of the most extensively explored
areas of research that has promising applications in therapeutics. As an endogenous …

[PDF][PDF] Silenciamiento de los genes GdMre11 y GdDmc1B en trofozoítos de Giardia duodenalis

V Flores, L Edel - 2016 - repositorio.cinvestav.mx
Giardia duodenalis (sin. Giardia lamblia, Giardia intestinalis), es un microorganismo
eucarionte unicelular flagelado al cual se le adjudica comúnmente síndrome diarreico …

[PDF][PDF] Chapter-8 RNA Interference-Mechanisms and Applications in Plant Pathology

GV Krishna - Chief Editor, 2021 - researchgate.net
Plant diseases are threat to world agriculture. Significant yield losses occur due to attack of
pathogens in most of the agricultural and horticultural crop species. More than 70 per cent of …

ATP-binding cassette subfamily C (ABCC) transporter 1 (ABCC1) and 4 (ABCC4) independent of their drug efflux ability affects breast cancer biology

F Low - 2019 - publications.aston.ac.uk
Breast cancer treatment has been a challenge to date, due in part to cancer cells acquiring
drug resistance. One of the mechanisms by which resistance can occur is the …

[PDF][PDF] Gene Silencing Strategies in Cancer Therapy: An Update for Drug Resistance

B Baradaran - Current Medicinal Chemistry, 2018 - researchgate.net
RNAi, post-transcriptional gene silencing mechanism, could be considered as one of the
most important breakthroughs and rapidly growing fields in science. Researchers are trying …

[PDF][PDF] Screening of cassava improved germplasm for potential resistance against cassava mosaic disease

DTK Mvududu - 2017 - wiredspace.wits.ac.za
With growing populations and climate change associated drought predicted for the future,
cassava can provide one solution for food security and a source of starch for industrial use …