Immunology of parasitic helminth infections

AS MacDonald, MI Araujo, EJ Pearce - Infection and immunity, 2002 - Am Soc Microbiol
Parasitic helminths, or worms, comprise a diverse group of metazoan organisms that infect
billions of people and their domesticated animals worldwide (22). In large part …

Class and subclass selection in parasite-specific antibody responses

O Garraud, R Perraut, G Riveau, TB Nutman - Trends in parasitology, 2003 - cell.com
Antibodies are characteristically induced in many parasitic infection processes. The class
and subclass of the antibody response is instrumental because each isotype has a distinct …

Symptomatic human neurocysticercosis: age, sex and exposure factors relating with disease heterogeneity

A Fleury, A Dessein, PM Preux, M Dumas, G Tapia… - Journal of …, 2004 - Springer
Objective: To evaluate the relevance of exposure and host biological factors in the
heterogeneity of the clinical, radiological and inflammatory picture of neurocysticercosis …

IFN-gamma and TNF associated with severe falciparum malaria infection in Saudi pregnant women

A Nasr, G Allam, O Hamid, A Al-Ghamdi - Malaria journal, 2014 - Springer
Background Tumour necrosis factor (TNF) and interferon gamma (IFN-γ), encoded by TNF-
836 C/A (rs 1800630) and IFN-γ-1616 C/T (rs2069705) genes, are key immunological …

Single gene effects in mouse models of host: pathogen interactions

A Fortier, G Min-Oo, J Forbes… - Journal of leukocyte …, 2005 - academic.oup.com
Inbred mouse strains have been known for many years to vary in their degree of
susceptibility to different types of infectious diseases. The genetic basis of these interstrain …

Association of the Gene Polymorphisms IFN-γ +874, IL-13 −1055 and IL-4 −590 with Patterns of Reinfection with Schistosoma mansoni

MR Gatlin, CL Black, PN Mwinzi… - PLoS Neglected …, 2009 - journals.plos.org
Background The immunologic findings that most consistently correlate with resistance in
human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped …

[HTML][HTML] Investigating the underlying mechanism of resistance to Ascaris infection

C Dold, CV Holland - Microbes and infection, 2011 - Elsevier
The generative mechanism (s) of predisposition to Ascaris infection are currently unknown.
While many factors play a role in interindividual infection intensity, much focus has been …

Overview of human genetic susceptibility to malaria: From parasitemia control to severe disease

S Marquet - Infection, Genetics and Evolution, 2018 - Elsevier
Malaria is a life-threatening blood disease caused by the protozoan Plasmodium. Infection
may lead to several different patterns of symptoms in the host: asymptomatic state …

Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns

AG Lokossou, C Dechavanne, A Bouraïma… - BMC infectious …, 2013 - Springer
Background Particular cytokine gene polymorphisms are involved in the regulation of the
antibody production. The consequences of already described IL-4, IL-10 and IL-13 gene …

Factors controlling the effect of praziquantel on liver fibrosis in Schistosoma mansoni-infected patients

SA Rahoud, A Mergani, AH Khamis… - FEMS Immunology & …, 2010 - academic.oup.com
An association study of a cohort of 177 Sudanese patients infected with Schistosoma
mansoni [82 (46%) males and 95 (54%) females] was conducted to evaluate the factors …