RNAs in cells are associated with RNA-binding proteins (RBPs) to form ribonucleoprotein
(RNP) complexes. The RBPs influence the structure and interactions of the RNAs and play …

Beyond the well-known function of poly (A) tail length in mRNA stability, recent years have
witnessed an explosion of information about how changes in tail length and the selection of …

Nearly two decades ago, Xenopus oocytes were found to contain mRNAs harboring a small
sequence in their 3′ untranslated regions that control cytoplasmic polyadenylation and …

Poly (A) tails have long been known as stable 3′ modifications of eukaryotic mRNAs,
added during nuclear pre‐mRNA processing. It is now appreciated that this modification is …

Cytoplasmic polyadenylation plays a key role in the translational control of mRNAs driving
biological processes such as gametogenesis, cell-cycle progression, and synaptic plasticity …

RNA-binding proteins (RBPs) are key regulators in post-transcriptional control of gene
expression. Mutations that alter their activity or abundance have been implicated in …

Poly (A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called
cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has …

We show that microRNA-427 (miR-427) mediates the rapid deadenylation of maternal
mRNAs after the midblastula transition (MBT) of Xenopus laevis embryogenesis. By MBT …

Elongation of the poly (A) tails of specific mRNAs in the cytoplasm is a crucial regulatory step
in oogenesis and early development of many animal species. The best studied example is …

Cytoplasmic elongation of the poly (A) tail was originally identified as a mechanism to
activate maternal mRNAs, stored as silent transcripts with short poly (A) tails, during meiotic …