Repurposing approved non-antitumor drugs is a promising and affordable strategy in drug
discovery to identify new therapeutic uses different from the original medical indication that …

Background Standard therapy for newly diagnosed glioblastoma is radiotherapy plus
temozolomide. In this phase 3 study, we evaluated the effect of the addition of bevacizumab …

This guideline provides recommendations for diagnostic and therapeutic procedures for
patients with malignant gliomas. We differentiate evidence-based standards from …

Glioblastoma is associated with a poor prognosis. Even though survival statistics are well-
described at the population level, it remains challenging to predict the prognosis of an …

Purpose The optimal radiotherapy regimen for elderly and/or frail patients with newly
diagnosed glioblastoma remains to be established. This study compared two radiotherapy …

Background: Glioblastom am ultiforme (GBM) is th em ost common and aggressive primary
intracranial tumor. Despit em odern therapies, it is still fatal with tremendously poor …

Importance Tumor-treating fields (TTFields) therapy improves both progression-free and
overall survival in patients with glioblastoma. There is a need to assess the influence of …

A detailed characterization study is presented of a Raman spectroscopy system designed to
maximize the volume of resected cancer tissue in glioma surgery based on in vivo molecular …

Treatment of glioblastoma (GBM), the most common primary malignant brain tumor in adults,
remains a significant unmet need in oncology. Historically, cytotoxic treatments provided …

Purpose As glioblastoma progresses, patients experience a decline in health-related quality
of life (HRQoL). Delaying this decline is an important treatment goal. In newly diagnosed …