It has been long recognized that NOD1 and NOD2 are critical players in the host immune
response, primarily by their sensing bacterial peptidoglycan‐conserved motifs. Significant …

Type 1 diabetes is considered to be an autoimmune disease in which T lymphocytes
infiltrate the islets of pancreas and destroy the insulin producing beta cell population …

This paper describes the methodology, results and limitations of the 2013 International
Diabetes Federation (IDF) Atlas (6th edition) estimates of the worldwide numbers of …

Background Finland has the highest incidence of type 1 diabetes worldwide, reaching 40
per 100 000 people per year in the 1990s. Our aim was to assess the temporal trend in type …

Case-control studies have shown an association between low birth weight and risk for renal
failure. The Medical Birth Registry of Norway, which comprises data on all births in Norway …

The primary objective of this multicenter, multinational, epidemiological study is the
identification of infectious agents, dietary factors, or other environmental exposures that are …

Type 1 diabetes is an immune-mediated disease characterized by a preclinical prodrome
during which β cell autoimmunity proceeds at a variable rate. Large geographic differences …

Diabetes mellitus is a worldwide epidemic affecting the health of millions of people. While
type 1 diabetes (T1D) is caused by autoimmune destruction of the insulin-producing beta …

Background: Studies have shown that the prevalence of children born with high birth weight
or large for gestational age (LGA) is increasing. This is true for spontaneous pregnancies; …

Previous studies suggest that birth weight and weight gain during the first year of life are
related to later risk of type 1 diabetes. The authors performed a systematic review and meta …