The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Recent research using Drosophila melanogaster has seen a resurgence in studies of
metabolism and physiology. This review focuses on major methods used to conduct this …

Although the gut is a central organ of Eumetazoans and is essential for organismal health,
our understanding of its morphological and molecular determinants remains rudimentary …

The digestive tract plays a central role in the digestion and absorption of nutrients. Far from
being a passive tube, it provides the first line of defense against pathogens and maintains …

Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

The Drosophila midgut is maintained throughout its length by superficially similar,
multipotent intestinal stem cells that generate new enterocytes and enteroendocrine cells in …

The production of offspring is energetically costly and relies on incompletely understood
mechanisms that generate a positive energy balance. In mothers of many species, changes …

The intestine is a key organ for lipid uptake and distribution, and abnormal intestinal lipid
metabolism is associated with obesity and hyperlipidemia. Although multiple regulatory gut …

Disruptions in energy homeostasis severely affect reproduction in many organisms and are
linked to several reproductive disorders in humans. As a result, understanding the …