Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Electrical synaptic transmission through gap junctions underlies direct and rapid neuronal
communication in the CNS. The diversity of functional roles that electrical synapses have is …

Connexins (Cxs) form hemichannels and gap junction channels. Each gap junction channel
is composed of two hemichannels, also termed connexons, one from each of the coupled …

Gap junctions establish direct pathways for cell-to-cell communication through the assembly
of twelve connexin subunits that form intercellular channels connecting neighbouring cells …

The cells of most mammalian organs are connected by groups of cell-to-cell channels called
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …

Gap junctions are unique intercellular channels that connect the cytoplasm of adjacent cells.
They are the only channels that mediate the direct cytoplasmic exchange of small …

Gap junctions (GJs) are the only known cellular structures that allow a direct cell-to-cell
transfer of signaling molecules by forming densely packed arrays or “plaques” of hydrophilic …

Connexin genes encode intercellular channels that help to coordinate development. In mice,
the targeted deletion of different connexins produces disparate effects on ocular growth and …

There are several reasons that one might want to selectively do away with gap junction
channels. Of critical importance to electrophysiologists, coupling interferes with …

We demonstrate that the antimalarial drug quinine specifically reduces currents through gap
junctions formed by some connexins (Cx) in transfected mammalian cells, but does not affect …