Identifying adaptive loci can provide insight into the mechanisms underlying local
adaptation. Genotype–environment association (GEA) methods, which identify these loci …

The observation that small isolated populations often suffer reduced fitness from inbreeding
depression has guided conservation theory and practice for decades. However …

Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse
high-throughput experiments. g: Profiler studies flat and ranked gene lists and finds …

The dog is our oldest domesticate and has experienced a wide variety of demographic
histories, including a bottleneck associated with domestication and individual bottlenecks …

The evolutionary history of the wolf-like canids of the genus Canis has been heavily
debated, especially regarding the number of distinct species and their relationships at the …

Genetic population assignment used to inform wildlife management and conservation efforts
requires panels of highly informative genetic markers and sensitive assignment tests. We …

Population genomics is advancing our understanding of evolution, ecology, conservation,
agriculture, forestry, and human health by allowing new and long-standing questions to be …

After decades of discussion, there is little consensus on the extent to which hybrids between
endangered and nonendangered species should be protected by US law. As increasingly …

We know much about pathogen evolution and the emergence of new disease strains, but
less about host resistance and how it is signaled to other individuals and subsequently …

Abstract The International Mouse Phenotyping Consortium (IMPC) is building a catalogue of
mammalian gene function by producing and phenotyping a knockout mouse line for every …