Alloimmunisation against red blood cells in sickle cell disease: transfusion challenges in high-income and low-income countries

F Pirenne, A Floch, S Diop - The Lancet Haematology, 2023 - thelancet.com
Sickle cell disease is the most frequent inherited disorder in sub-Saharan Africa and in many
high-income countries (HICs). Transfusion is a key element of treatment, but it results in high …

Blood donors with thalassemic trait, glucose-6-phosphate dehydrogenase deficiency trait, and sickle cell trait and their blood products: current status and future …

E Noulsri, S Lerdwana - Laboratory Medicine, 2023 - academic.oup.com
The use of blood products for different medical purposes has increased in recent years. To
meet increasing demand, some blood centers allow volunteer donors with thalassemic trait …

Comorbidity of glucose‐6‐phosphate dehydrogenase deficiency and sickle cell disease exert significant effect on RBC indices

S Antwi-Baffour, JK Adjei, PO Forson, S Akakpo… - Anemia, 2019 - Wiley Online Library
Background. Glucose‐6‐phosphate dehydrogenase (G6PD) converts glucose‐6‐phosphate
into 6‐phosphogluconate in the pentose phosphate pathway and protects red blood cells …

Hemoglobin S and glucose-6-phosphate dehydrogenase deficiency coinheritance in AS and SS individuals in malaria-endemic region: a study in Calabar, Nigeria

IM Okafor, HU Okoroiwu, CA Ekechi - Journal of Global Infectious …, 2019 - journals.lww.com
Background: Malaria placed a huge burden on human life and has been reported to be a
key health problem affecting developing countries. This study was designed to assay for …

Storage related haematological and biochemical changes in Plasmodium falciparum infected and sickle cell trait donor blood

E Aninagyei, ET Doku, P Adu, A Egyir-Yawson… - BMC hematology, 2018 - Springer
Abstract Background In sub-Saharan Africa where sickle cell trait (SCT) and malaria is
prevalent, significant proportions of blood donors may be affected by one or more of these …

Genotypic glucose-6-phosphate dehydrogenase (G6PD) deficiency protects against Plasmodium falciparum infection in individuals living in Ghana

LE Amoah, KK Asare, D Dickson, J Abankwa… - PloS one, 2021 - journals.plos.org
Introduction The global effort to eradicate malaria requires a drastic measure to terminate
relapse from hypnozoites as well as transmission via gametocytes in malaria-endemic …

Anaemia Prevalence More Than Doubles in an Academic Year in a Cohort of Tertiary Students: A Repeated‐Measure Study in Cape Coast, Ghana

RE Amoaning, ES Amoako, GA Kyiire… - Advances in …, 2022 - Wiley Online Library
Background. The stress of academic life may predispose young adults to poor dietary habits,
which could potentially precipitate nutritional deficiencies, such as iron deficiency. This study …

Carrier frequency and molecular basis of hemoglobinopathies among blood donors in eastern Morocco: Implications for blood donation and genetic diagnosis

I Belmokhtar, KY Belmokhtar, S Lhousni, M Charif… - Clinical …, 2025 - Elsevier
Background Hemoglobinopathies represent the most commonly inherited autosomal
recessive blood disorders in the world. The aim of this study was to determine the carrier …

Co-Occurrence of G6PD Deficiency and SCT among Pregnant Women Exposed to Infectious Diseases

GK Helegbe, A Wemakor, EPK Ameade… - Journal of Clinical …, 2023 - mdpi.com
During pregnancy, women have an increased relative risk of exposure to infectious
diseases. This study was designed to assess the prevalence of the co-occurrence of glucose …

[HTML][HTML] Reduction of Missed Diagnosis of G6PD Deficiency in Heterozygous Females by G6PD/6PGD Ratio Assay Combined with Amplification Refractory Mutation …

S Chen, J Gao, Q Wu, X Li, S Lin, J Su, K Zheng… - Human Heredity, 2023 - karger.com
Objective: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic
disorder that results in impaired enzyme activity. The G6PD/6PGD ratio assay was routinely …