[HTML][HTML] Autophagy orchestrates resistance in hepatocellular carcinoma cells

H Seydi, K Nouri, N Rezaei, A Tamimi… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment resistance is one of the major barriers for therapeutic strategies in
hepatocellular carcinoma (HCC). Many studies have indicated that chemotherapy and …

Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy

MY Zamanian, M Golmohammadi… - Fundamental & …, 2023 - Wiley Online Library
Background Tamoxifen (TAM) is often recommended as a first‐line treatment for estrogen
receptor‐positive breast cancer (BC). However, TAM resistance continues to be a medical …

[HTML][HTML] Multi-omics analysis revealed a significant alteration of critical metabolic pathways due to sorafenib-resistance in Hep3B cell lines

KYI Abushawish, SSM Soliman, AD Giddey… - International Journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the second prominent cause of cancer-associated death
worldwide. Usually, HCC is diagnosed in advanced stages, wherein sorafenib, a multiple …

[HTML][HTML] Choline suppresses hepatocellular carcinoma progression by attenuating AMPK/mTOR-mediated autophagy via choline transporter SLC5A7 activation

C Wang, ZY Liu, WG Huang, ZJ Yang… - Hepatobiliary …, 2024 - hbsn.amegroups.org
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-
associated death. Emerging evidence suggests that autophagy plays a critical role in HCC …

[HTML][HTML] Xiaochaihu decoction induces Bel-7402/5-FU cell apoptosis and autophagy via PI3K/AKT/mTOR pathway

X Zhang, S Chen, X Wang, J Peng, J Lin… - Journal of Holistic …, 2023 - Elsevier
Objective This study aimed to observe the inhibitory effects of xiaochaihu decoction (XCHD)
on human hepatocellular carcinoma (HCC) cells resistant to 5-fluorouracil (5-FU)(Bel …