Purified allergens are named using the systematic nomenclature of the Allergen
Nomenclature Sub-Committee of the World Health Organization and International Union of …

While asthma is an inflammatory disorder of the airways usually associated with atopy, an
important additional component is involvement of the epithelium and underlying …

House dust mites are a significant source of airborne allergen worldwide, but there is little
understanding of how they so potently generate allergic inflammation. We found that extracts …

BACKGROUND: The body of sequence and structural information on allergens and the
sequence analysis of whole plant genomes are facilitating the application of bioinformatic …

We investigated and compared the mechanisms by which two dust mite proteolytic
allergens, Der p 1 and Der p 3, and a peptide agonist of proteinase-activated receptor 2 …

Several cysteine and serine protease allergens have been cloned from house dust mites,
including Der p 1, Der p 3, Der p 6, and Der p 9. A significant body of evidence suggests that …

Classic studies in sheep have contributed greatly to our understanding of lung physiology in
health and disease. Similarities in size and structure between sheep and human lungs allow …

Background Remodelling of airway walls is a significant morbidity factor in patients suffering
from chronic asthma. The relationship between airway remodelling and the inflammatory …

House dust mite (HDM) is a common allergen of allergic asthma. Eosinophils are principal
effector cells of allergic inflammation and their adhesion onto human bronchial epithelial …

A number of environmental factors can affect the development and severity of allergy and
asthma; however, it can be argued that the most significant inhaled agents that modulate the …