Applications of proteomics in ovarian cancer: dawn of a new era

A Ghose, SVN Gullapalli, N Chohan, A Bolina… - Proteomes, 2022 - mdpi.com
The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …

BRCA mutations in ovarian and prostate cancer: bench to bedside

S Boussios, E Rassy, M Moschetta, A Ghose… - Cancers, 2022 - mdpi.com
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …

Recent insights into PARP and immuno-checkpoint inhibitors in epithelial ovarian cancer

A Revythis, A Limbu, C Mikropoulos, A Ghose… - International journal of …, 2022 - mdpi.com
Ovarian cancer is one of the most common gynecologic cancers and has the highest
mortality rate of any other cancer of the female reproductive system. Epithelial ovarian …

Epithelial ovarian cancer: providing evidence of predisposition genes

S Shah, A Cheung, M Kutka, M Sheriff… - International Journal of …, 2022 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …

Advances in ovarian cancer treatment beyond PARP inhibitors

F Aliyuda, M Moschetta, A Ghose… - Current Cancer Drug …, 2023 - ingentaconnect.com
Ovarian cancer has become the largest cause of gynaecological cancer-related mortality. It
is typically diagnosed at a late stage and has no effective screening strategy. Ovarian cancer …

Hereditary ovarian cancer: towards a cost-effective prevention strategy

A Ghose, A Bolina, I Mahajan, SA Raza… - International Journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is the most lethal gynaecological malignancy. The search for a widely
affordable and accessible screening strategy to reduce mortality from OC is still ongoing …

Clinical challenges in the management of malignant ovarian germ cell tumours

I Saani, N Raj, R Sood, S Ansari… - International journal of …, 2023 - mdpi.com
Nonepithelial ovarian cancers (NEOC) are a group of rare malignancies, including germ cell
tumours (GCT) and sex cord-stromal tumours (SCST), along with small-cell carcinomas and …

Diagnostic biomarkers in ovarian cancer: advances beyond CA125 and HE4

A Ghose, L McCann, S Makker… - … in medical oncology, 2024 - journals.sagepub.com
Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

Maintenance therapy for newly diagnosed epithelial ovarian cancer–a review

S Nag, S Aggarwal, A Rauthan, N Warrier - Journal of ovarian research, 2022 - Springer
Epithelial ovarian cancer (EOC) is the most lethal gynaecological cancer among women
worldwide, with the 5-year survival rate ranging between 30 and 40%. Due to the …

[HTML][HTML] Deep learning can predict bevacizumab therapeutic effect and microsatellite instability directly from histology in epithelial ovarian cancer

CW Wang, YC Lee, YJ Lin, NP Firdi, H Muzakky… - Laboratory …, 2023 - Elsevier
Epithelial ovarian cancer (EOC) remains a significant cause of mortality among gynecologic
cancers, with the majority of cases being diagnosed at an advanced stage. Before targeted …