Chronic rhinosinusitis (CRS) is a persistent inflammatory disease of the nasal cavity and
paranasal sinuses. Traditional classification is denoted by the presence (CRSwNP) or …

Semaphorins are a group of proteins that have been studied extensively for their critical
function in neuronal development. They have been shown to regulate airway development …

Activated microglia in the retina are essential for the development of autoimmune uveitis. Yin‐
Yang 1 (YY1) is an important transcription factor that participates in multiple inflammatory …

This review highlights recent advances in the understanding of eosinophils and eosinophilic
diseases, particularly eosinophilic gastrointestinal diseases during the last year. The …

Major progress has been achieved in the understanding and clinical practice of chronic
rhinosinusitis, with or without nasal polyps. These advances resulted in a better …

In vertebrates, the semaphorin family of proteins is composed of 21 members that are
divided into five subfamilies, ie classes 3 to 7. Semaphorins play crucial roles in regulating …

abstract Semaphorins were originally identified as guidance molecules in neural
development. However, accumulating evidence indicates that 'immune semaphorins' are …

Inflammation of endothelial cells (ECs) plays an important role in the pathogenesis of
coronary artery lesions (CALs) in Kawasaki disease (KD). Semaphorin 4D (Sema4D) is the …

Abstract Semaphorin 4D (Sema4D) is highly expressed in a variety of tumors and is
associated with high invasion, poor prognosis and poor therapeutic response. However, the …

Eosinophilic chronic rhinosinusitis (ECRS) is a Type 2 inflammatory disease that manifests
as chronic inflammation of the paranasal sinus. IL-4/IL-13 receptor monoclonal antibodies …