Objectives/Hypothesis To perform a systematic review of GJB2‐associated hearing loss to
describe genotype distributions and auditory phenotype. Data Sources 230 primary studies …

Objective: The mutation spectrum of the GJB2 and SLC26A4 genes, the 2 most common
genes causing deafness, are known to be ethnic specific. In this study, the spectrum of the …

Hearing impairment not etiologically associated with clinical signs in other organs (non-
syndromic) is genetically heterogeneous, so that over 120 genes are currently known to be …

Hearing loss (HL) is the most prevalent sensory defect affecting 1 in 500 neonates. Genetic
factors are involved in half of the cases. The extreme heterogeneity of HL makes it difficult to …

The incidence of hearing impairment (HI) is higher in low-and middle-income countries
when compared to high-income countries. There is therefore a necessity to estimate the …

Обоснована необходимость органосохраняющих и органозамещающих операций при
травматических повреждениях селезенки, изучено состояние пациентов в различные …

Genetic variants in GJB 2 and GJB 6 genes are the most frequent causes of hereditary
hearing loss among several deaf populations worldwide. Molecular diagnosis enables …

Pathogenic variants in the GJB2 gene, encoding connexin 26, are known to be a major
cause of hearing impairment (HI). More than 300 allelic variants have been identified in the …

Autosomal recessive non-syndromic hearing loss (ARNSHL) is a public health concern in
the Iranian population, with an incidence of 1 in 166 live births. In the present study, the …

Objective Hereditary hearing loss (HL) is a noticeable concern in medicine all over the
world. On average, 1 in 166 babies born are diagnosed with HL in Iran, which makes it a …