2022 update on prostate cancer epidemiology and risk factors—a systematic review

O Bergengren, KR Pekala, K Matsoukas, J Fainberg… - European urology, 2023 - Elsevier
Abstract Context Prostate cancer (PCa) is one of the most common cancers worldwide.
Understanding the epidemiology and risk factors of the disease is paramount to improve …

The role of hepatokines in NAFLD

N Stefan, F Schick, AL Birkenfeld, HU Häring, MF White - Cell metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis

A Mantovani, A Csermely, G Petracca… - The lancet …, 2021 - thelancet.com
Background Studies have reported a significant association between non-alcoholic fatty liver
disease (NAFLD) and increased incidence of cardiovascular disease (CVD). However, the …

Tumour extracellular vesicles and particles induce liver metabolic dysfunction

G Wang, J Li, L Bojmar, H Chen, Z Li, GC Tobias, M Hu… - Nature, 2023 - nature.com
Cancer alters the function of multiple organs beyond those targeted by metastasis,. Here we
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …

Current therapies and new developments in NASH

JF Dufour, QM Anstee, E Bugianesi, S Harrison… - Gut, 2022 - gut.bmj.com
Non-alcoholic steatohepatitis is becoming the most important aetiology for advanced liver
disease. There has been important progress in the field in recent years and the complexity of …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

the epidemiologic burden of non‐alcoholic fatty liver disease across the world

L Henry, J Paik, ZM Younossi - Alimentary pharmacology & …, 2022 - Wiley Online Library
Background The prevalence of non‐alcoholic fatty liver disease (NAFLD) is increasing in
parallel with obesity and type 2 diabetes. Aim To review the global epidemiology of NAFLD …

MAFLD: A multisystem disease

RM Pipitone, C Ciccioli, G Infantino… - Therapeutic …, 2023 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

Healthcare and socioeconomic costs of NAFLD: A global framework to navigate the uncertainties

AM Allen, JV Lazarus, ZM Younossi - Journal of hepatology, 2023 - Elsevier
Left unaddressed, non-alcoholic fatty liver disease (NAFLD) will continue to have substantial
health, economic and social implications. To address the challenge, a paradigm shift is …