Nematodes pervade Earth's biosphere and occupy innumerable ecological niches. The role
of Caenorhabditis elegans as a model for developmental processes has encouraged us to …

Here we present a brief, historical review of research into the mammalian middle ear
structures. Most of their essential homologies were established by embryologists, notably …

Here we present a draft genome sequence of the nematode Pristionchus pacificus, a
species that is associated with beetles and is used as a model system in evolutionary …

Although there has been extensive characterization of the Wnt signaling pathway in the
osteoblast lineage, the effects of Wnt proteins on the osteoclast lineage are less well …

Background A surprising amount of developmental variation has been observed for
otherwise highly conserved features, a phenomenon known as developmental system drift …

Evolutionary developmental biology examines how changes in developmental programmes
give rise to developmental and, ultimately, morphological novelty. To this end, comparisons …

Biologists have long appreciated natural variation in the nematode phylum. The
development of Caenorhabditis elegans as a model organism has provided a rich set of …

Pristionchus pacificus has been developed as a nematode satellite organism in evolutionary
developmental biology. Detailed studies of vulva development revealed multiple differences …

Mutational robustness facilitates evolutionary innovations. Gene duplications are unique
kinds of mutations, in that they generally increase such robustness. The frequent association …

Abstract Background The nematode Pristionchus pacificus has originally been developed as
a satellite organism for comparison to Caenorhabditis elegans. A 10X coverage of the whole …