Stress-related synaptic plasticity in the hypothalamus

JS Bains, JIW Cusulin, W Inoue - Nature Reviews Neuroscience, 2015 - nature.com
Stress necessitates an immediate engagement of multiple neural and endocrine systems.
However, exposure to a single stressor causes adaptive changes that modify responses to …

Impacts of stress and sex hormones on dopamine neurotransmission in the adolescent brain

D Sinclair, TD Purves-Tyson, KM Allen… - Psychopharmacology, 2014 - Springer
Rationale Adolescence is a developmental period of complex neurobiological change and
heightened vulnerability to psychiatric illness. As a result, understanding factors such as sex …

Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity

JS Kim, SY Han, KJ Iremonger - Nature communications, 2019 - nature.com
Stress leaves a lasting impression on an organism and reshapes future responses.
However, the influence of past experience and stress hormones on the activity of neural …

Glucocorticoid hormones are both a major circadian signal and major stress signal: How this shared signal contributes to a dynamic relationship between the …

RL Spencer, LE Chun, MJ Hartsock… - Frontiers in …, 2018 - Elsevier
Glucocorticoid hormones are a powerful mammalian systemic hormonal signal that exerts
regulatory effects on almost every cell and system of the body. Glucocorticoids act in a …

The physiological roles of placental corticotropin releasing hormone in pregnancy and childbirth

M Thomson - Journal of physiology and biochemistry, 2013 - Springer
In response to stress, the hypothalamus releases cortiticotropin releasing hormone (CRH)
that travels to the anterior pituitary, where it stimulates the release of adrenocorticotropic …

Stress-induced glucocorticoid desensitizes adrenoreceptors to gate the neuroendocrine response to somatic stress in male mice

Z Jiang, C Chen, GL Weiss, X Fu, CE Stelly… - Cell reports, 2022 - cell.com
Noradrenergic afferents to hypothalamic corticotropin releasing hormone (CRH) neurons
provide a major excitatory drive to the hypothalamic-pituitary-adrenal (HPA) axis via α1 …

Role of nitric oxide in stress-induced anxiety: from pathophysiology to therapeutic target

A Kumar, P Chanana - Vitamins and hormones, 2017 - Elsevier
Stress is often marked by a state of hyperarousal to aid the initiation of necessary stress
response for the successful management of stressful stimuli. It can be manifested as a …

Corticotropin releasing factor in neuroplasticity

L Regev, TZ Baram - Frontiers in neuroendocrinology, 2014 - Elsevier
Stress is among the strongest signals promoting neuroplasticity: Stress signals, indicating
real or perceived danger, lead to alterations of neuronal function and often structure …

Response of the nitrergic system to activation of the neuroendocrine stress axis

HJC Chen, JG Spiers, C Sernia… - Frontiers in neuroscience, 2015 - frontiersin.org
Exposure to stressful stimuli causes activation of the hypothalamic-pituitary-adrenal axis
which rapidly releases high concentrations of glucocorticoid stress hormones, resulting in …

Mechanisms underlying the increased plasma ACTH levels in chronic psychosocially stressed male mice

AM Füchsl, D Langgartner, SO Reber - PloS one, 2013 - journals.plos.org
Mice exposed to chronic subordinate colony housing (CSC, 19 days), an established
paradigm for chronic psychosocial stress, show unaffected basal morning plasma …