ABSTRACT Echinocandins (caspofungin, micafungin, anidulafungin), targeting β-1, 3-
glucan synthesis of the cell wall, represent one of the three currently available antifungal …

Germination of conidia is an essential process within the Aspergillus life cycle and plays a
major role during the infection of hosts. Conidia are able to avoid detection by the majority of …

Azole antifungals inhibit the fungal ergosterol biosynthesis pathway, resulting in either
growth inhibition or killing of the pathogen, depending on the species. Here we report that …

MADS-box transcription factors (TFs), among the first TFs extensively studied, exhibit a wide
distribution across eukaryotes and play diverse functional roles. Varying by domain …

The maintenance of cell-wall integrity (CWI) is important for mycelial growth, development,
and pathogenicity in fungi. Arthrobotrys oligospora is a typical nematode-trapping (NT) …

To gain a better understanding of the transcriptional response of Aspergillus fumigatus
during invasive pulmonary infection, we used a NanoString nCounter to assess the …

Inhibition of fungal growth by Congo red (CR) has been putatively associated with specific
binding to β-1, 3-glucans, which blocks cell wall polysaccharide synthesis. In this study, we …

Aspergillus fumigatus is an opportunistic fungal pathogen that causes invasive aspergillosis
(IA), a life-threatening disease in immunocompromised humans. The echinocandin …

The pathogenic fungus Aspergillus fumigatus is able to adapt to extremely variable
environmental conditions. The A. fumigatus genome contains four genes coding for mitogen …

Aspergillus nidulans is an opportunistic fungal pathogen in patients with immunodeficiency,
and virulence of A. nidulans isolates has mainly been studied in the context of chronic …