CB Mishra, M Tiwari, CT Supuran - Medicinal Research …, 2020 - Wiley Online Library
Abstract Carbonic anhydrases (CAs, EC 4.2. 1.1) are widely distributed metalloenzymes in both prokaryotes and eukaryotes. They efficiently catalyze the reversible hydration of carbon …
V Alterio, A Di Fiore, K D'Ambrosio, CT Supuran… - Chemical …, 2012 - ACS Publications
Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene …
S Kumar, S Rulhania, S Jaswal, V Monga - European journal of medicinal …, 2021 - Elsevier
Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …
CT Supuran - Expert opinion on therapeutic patents, 2018 - Taylor & Francis
The metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1) is ubiquitously expressed in organisms all over the phylogenetic tree, with seven genetically distinct families known to …
At least 14 different carbonic anhydrase (CA, EC 4.2. 1.1) isoforms were isolated in higher vertebrates, where these zinc enzymes play crucial physiological roles. Some of these …
A Scozzafava, T Owa, A Mastrolorenzo… - Current medicinal …, 2003 - ingentaconnect.com
The sulfonamides constitute an important class of drugs, with several types of pharmacological agents possessing antibacterial, anti-carbonic anhydrase, diuretic …
Introduction: Glaucoma is one of the major causes of blindness, affecting together with age- related macular degeneration> 70 million people worldwide. One of the therapeutic options …
Carbonic anhydrases (CAs, EC 4.2. 1.1) are zinc enzymes acting as efficient catalysts for the reversible hydration of carbon dioxide to bicarbonate. 16 different α-CA isoforms were …
F Carta, CT Supuran - Expert opinion on therapeutic patents, 2013 - Taylor & Francis
Introduction: The benzothiadiazines and high ceiling diuretics (hydrochlorothiazide, hydroflumethiazide, quinethazone, metolazone, chlorthalidone, indapamide, furosemide …