Recent green chemistry approaches for pyrimidine derivatives as a potential anti-cancer agent: An overview (2013–2023)
The widespread scrutiny of orthodox synthetic techniques for the fabrication of nitrogen-
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …
[HTML][HTML] Inflammation and late-life depression: unraveling the complex relationship and potential therapeutic strategies
J Xia, M Chen, H Shao, H Chen, S Zhu… - Frontiers in Bioscience …, 2023 - imrpress.com
The origins of late-life depression are multifaceted and remain challenging to fully
understand. While the traditional monoamine neurotransmitter hypothesis provides some …
understand. While the traditional monoamine neurotransmitter hypothesis provides some …
A novel animal model of tegafur-induced hand-foot syndrome
M Takano-Mochizuki, K Nakajima, T Ishida… - Toxicology and Applied …, 2024 - Elsevier
Hand-foot syndrome (HFS) is a common side effect of fluoropyrimidine anticancer drugs and
often becomes a dose-limiting manifestation of toxicity once it occurs. The precise …
often becomes a dose-limiting manifestation of toxicity once it occurs. The precise …
STING 高表达通过调控TLR4/NF-κB/NLRP3 通路和影响炎症与凋亡水平促进小鼠肾脏缺血再灌注损伤
陶怀祥， 骆金光， 闻志远， 虞亘明， 苏萧… - Journal of Southern …, 2024 - pmc.ncbi.nlm.nih.gov
目的探讨STING 在肾缺血再灌注损伤(IRI) 中的表达水平以及相关作用机制. 方法在体内水平,
将24 只C57BL/6 小鼠分为假手术组(Sham), IRI 组, IRI+ 药物溶剂组(IRI+ DMSO), IRI+ SN-011 …
将24 只C57BL/6 小鼠分为假手术组(Sham), IRI 组, IRI+ 药物溶剂组(IRI+ DMSO), IRI+ SN-011 …
TXB-001, a newly-developed polymer-conjugated anthracycline: Significantly lower adverse effects in animal models of alopecia and hand-foot syndrome
M Hirakata, E Tomikawa, C Sakai, M Uchida… - Toxicology and Applied …, 2024 - Elsevier
Anthracycline anti-cancer drugs have been widely used in the treatment of several cancers;
however, their use is limited by adverse effects (AEs). Alopecia is a common AE that is …
however, their use is limited by adverse effects (AEs). Alopecia is a common AE that is …
[HTML][HTML] Benefits of High-Dose Vitamin D in Managing Cutaneous Adverse Events Induced by Chemotherapy and Radiation Therapy
ML Muldowney, BE Shields - Cutis, 2024 - mdedge9-ma1.mdedge.com
V itamin D (VD) regulates keratinocyte proliferation and differentiation, modulates
inflammatory pathways, and protects against cellular damage in the skin. 1 In the setting of …
inflammatory pathways, and protects against cellular damage in the skin. 1 In the setting of …