India lacks a national policy on the prevention and control of genetic disorders. Although the
haemoglobinopathies have received some attention, there are scarce data on the …

Hemophilia A and B, inherited as X-linked recessive traits, are the most common hereditary
hemorrhagic disorders caused by a deficiency or dysfunction of coagulation factor VIII (FVIII) …

Heterogeneous mutations in factor IX (FIX) gene cause haemophilia B and a large number
of mutations have been characterized. However, reports on gene defects among Indian …

In families afflicted with haemophilia A, genetic counselling is often requested. Inversion
mutations and polymorphic sites of the FVIII gene have been examined in a Brazilian …

Little is known about the heterozygous frequency of factor VIII gene markers in the Asian
Indian population. The objective of this study was to establish the heterozygous frequency of …

Abstract During the last 10 years (1995–2005) we have offered diagnosis in 438 families out
of 502 families referred, by chorionic villus sampling procedure between 10 and 12 weeks of …

Hemophilia A is a common inherited X-linked bleeding disorder resulting from a wide variety
of mutations in the Factor VIII (FVIII) gene located on long arm of X-chromosome at the Xq28 …

Background. Haemophilias are the commonest X-linked disorders affecting approximately 1
in 10 000 male births. Detection of carrier women in families with haemophilia and …

Organizing services for haemophilia in developing countries with few resources is a
formidable task. There is wide variation in haemophilia care and management between …

Prenatal diagnosis is the generally accepted option for genetic disorders including
haemophilias and other bleeding disorders. Cord blood analysis between 17.4 and 20.6 …