To enhance infection, enveloped viruses exploit adhesion molecules expressed on the
surface of host cells. Specifically, phosphatidylserine (PS) receptors–including members of …

Twenty-five years ago, an aberrant HIV-1 (now classified as HIV-1 group O) was described
from a Cameroonian HIV patient living in Belgium. The epicenter of group O was later found …

We are facing the worldwide invasion of a new coronavirus. This follows several limited
outbreaks of related viruses in various locations in a recent past (SARS, MERS). Although …

Background Due to the prevalence of HIV-1 group M and the endemicity of HIV-1 group O
infections in Cameroon, patients may be infected with both viruses and/or with HIV-1/MO …

Background Simian immunodeficiency viruses (SIV) have been jumping between non-
human primates in West/Central Africa for thousands of years and yet, the HIV-1 epidemic …

Background Fostemsavir belongs to the new class of attachment inhibitors (AIs); it inhibits
the entry of HIV into CD4+ T-lymphocytes by blocking conformational changes in gp120 …

Transmissions of simian viruses to humans has originated the different groups of HIV-1. We
recently identified a functional motif (CLA), in the C-terminal domain of the integrase …

Background Therapeutic outcomes for patients infected by genetically divergent HIV-1/O are
not well-known due to scarce data and the lack of an appropriate comparison with patients …

Despite only 30,000 group O HIV-1 infections, a similar genetic diversity is observed among
the O subgroups H (head) and T (tail)(previously described as subtypes A, B) as in the 9 …

To eliminate HIV infection, there are several elements to take into account to limit
transmission and break viral replication, such as epidemiological, preventive or therapeutic …