HER2-directed therapy in advanced breast cancer: benefits and risks

P Mandó, F Waisberg, R Pasquinelli… - OncoTargets and …, 2023 - Taylor & Francis
Around 20% of breast cancers are associated with amplification or overexpression of human
epidermal growth factor receptor 2 (HER2). In this setting, anti-HER2-targeted agents are the …

Time to deterioration of patient-reported outcomes as a surrogate of overall survival: a meta-analysis

A Shahnam, U Nindra, J Desai, R Hui… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Overall survival is the optimal marker of treatment efficacy in randomized
clinical trials (RCTs) but can take considerable time to mature. Progression-free survival …

App-based lifestyle coaching (PINK!) accompanying breast cancer patients and survivors to reduce psychological distress and fatigue and improve physical activity: a …

J Wolff, P Wuelfing, A König, B Ehrl, J Damsch… - Breast Care, 2023 - karger.com
Introduction: This pilot study aimed to investigate the effects of using an app-based certified
medical product named PINK! on breast cancer patients and survivors. The objectives were …

Patient-Reported Quality of Life at Diagnosis in Adolescent and Young Adults With Cancer

GC George, C Andersen, X Tang, E Rodriguez… - Journal of the National …, 2024 - jnccn.org
Background: The overall landscape of health-related quality of life (HRQoL) has not been
thoroughly investigated in adolescents and young adults (AYAs) with cancer. Data are also …

App-based support for breast cancer patients to reduce psychological distress during therapy and survivorship-a multicentric randomized controlled trial

J Wolff, S Seidel, P Wuelfing, MP Lux… - Frontiers in …, 2024 - frontiersin.org
The negative impact of unmanaged psychological distress on quality of life and outcome in
breast cancer survivors has been demonstrated. Fortunately, studies indicate that distress …

[HTML][HTML] Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin …

A Trojan, S Roth, Z Atassi, M Kiessling… - JMIR cancer, 2024 - cancer.jmir.org
Background Trastuzumab has had a major impact on the treatment of human epidermal
growth factor receptor 2 (HER2)-positive breast cancer (BC). Anti-HER2 biosimilars such as …

The predictive value of patient-reported outcomes on the impact of breast cancer treatment-related quality of life

K Zhou, M Bellanger, S Le Lann, M Robert… - Frontiers in …, 2022 - frontiersin.org
Purpose Patient-reported outcomes (PROs) have been widely used to measure breast
cancer (BC) treatment outcomes. However, evidence is still limited on using routinely PROs …

Prediction of Five-Year Survival Rate for Rectal Cancer Using Markov Models of Convolutional Features of RhoB Expression on Tissue Microarray

TD Pham - IEEE/ACM Transactions on Computational Biology …, 2023 - ieeexplore.ieee.org
The ability to predict survival in cancer is clinically important because the finding can help
patients and physicians make optimal treatment decisions. Artificial intelligence in the …

Caracterización de pacientes con cáncer de mama con receptor 2 del factor de crecimiento epidérmico humano (her2) con resultado equívoco en un laboratorio de …

SD Ramírez Márquez - 2022 - repositorio.unisinucartagena.edu.co
Introducción: La expresión de HER2 equivoco en cáncer de mama tiene impacto negativo
en morbimortalidad. Objetivos: Establecer la caracterización de pacientes con cáncer de …