Proliferative vitreoretinopathy (PVR) is still a major cause of failure of retinal detachment
surgery. Despite a dramatic increase in our pathobiologic knowledge of PVR during the last …

Diabetic retinopathy continues to be the leading cause of legal blindness among working-
age individuals. The earliest histological features of diabetic retinopathy include neuroretinal …

Proliferative vitreoretinopathy (PVR) is a potentially blinding fibrotic complication. It is
caused by the formation and contraction of epiretinal membranes (ERMs) that ultimately …

The retinal pigment epithelium (RPE) is a partner of the neural retina and is indispensable
for vision. In humans, proliferation and transformation (cell-type switching) of RPE cells after …

Background Proliferative retinopathies are considered to represent maladapted retinal
wound repair processes driven by growth factor-and cytokine-induced overstimulation of …

Eye injury is a significant disabling worldwide health problem. Proliferative Vitreoretinopathy
(PVR) is a common complication that develops in up to 40–60% of patients with an open …

Because proliferative vitreoretinopathy cannot be effectively treated, its prevention is
indispensable for the success of surgery for retinal detachment. The elaboration of …

Proliferative vitreoretinopathy (PVR) is a blinding disorder that occurs in eyes with
rhegmatogenous retinal detachment and in eyes that have recently undergone retinal …

Proliferative vitreoretinopathy (PVR) is thought to represent an exaggerated and protracted
scarring process following rhegmatogenous retinal detachment (RD) and following RD …

Müller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of
functional interactions between neurons and Müller cells, including delivery of the light …