Local anesthetics are widely used clinically for perioperative analgesia to achieve comfort in
medical treatment. However, when the concentration of local anesthetics in the blood …

Local anesthetics, drugs that only affect a restricted area of the body, are widely used in
daily clinical practice. Less studied but equally important is the distribution of local …

In this work, magnetic tetraethylenepentamine (TEPA)-modified carboxyl–carbon nanotubes
were synthesized, characterized, and used as adsorbents to conduct magnetic solid-phase …

A high-performance liquid chromatography–tandem mass spectrometry (LC/MS/MS) with
electrospray ionization (ESI) procedure for the simultaneous determination of nine local …

Intravenous lipid emulsions (ILEs) have been used widely for the treatment of local
anesthetic (LA) poisoning and have been proposed as a treatment for intoxication by other …

Purpose To characterize clinical profile of pediatric local anesthetic (LA) systemic toxicity
(LAST) and to identify determinants of life-threatening outcomes. Methods Spontaneous …

A novel PRiME (process, robustness, improvements, matrix effects, ease of use) pass-
through cleanup procedure has been developed to improve the existing commercially …

Introdução: Toxicidade pode ser definida como a capacidade inerente e potencial do
agente tóxico de provocar efeitos nocivos em organismos vivos. O efeito tóxico é …

История о борьбе, поиске своего предназначения и открытии в себе того, что делает
человека поистине сильным. Сражаясь в эпических битвах, где каждая полна динамики …

La emulsiones lipídicas intravenosas (ELI) se han utilizado ampliamente para el tratamiento
de la intoxicación por anestésicos locales (AL) y se han propuesto como tratamiento de la …