The pyranopyrimidine core is a key precursor for medicinal and pharmaceutical industries due to its broader synthetic applications as well as its bioavailability. Among its four possible …
The cyclocondensation reaction of aldehydes with dimedone and bis (6‐aminopyrimidin‐4‐ one) in acetic acid led to the formation of the corresponding bis (pyrimido [4, 5‐b] quinoline …
The effective synthesis of bis (spirocyclic-2-oxindole) tethered to 10b-azachrysene or 10a- azaphenanthrene moieties via the Hantzsch-like reaction of phenylenebis (methylene)) bis …
Synthesis of analogs of known active compounds is the most often employed strategy for producing important compounds. The Hantzsch reaction was employed to create new star …
IMZ Fares, NE Mahmoud, IA Abdelhamid… - Results in …, 2024 - Elsevier
Bacterial infections are a global issue, causing sickness and death, mainly in developing nations. Resistance to current medicines is a significant issue in healthcare. Overcoming the …
Both 3‐aminothieno [2, 3‐b] pyridine‐2‐carboxamide derivative 4 and bis (3‐aminothieno [2, 3‐b] pyridine‐2‐carboxamide) derivative 6 are prepared, starting with pyridine‐2 (1H) …
Molecular hybridization is a technique used in drug creation that involves combining the pharmacophoric moieties of multiple bioactive compounds to create a new hybrid molecule …
AM Abdelmoniem, MA Ramadan, SAS Ghozlan… - …, 2023 - Wiley Online Library
Abstract New Azacycles by One‐Pot Three‐Component Hantzsch‐Like Synthesis of Tetra (hexa) azacyclopenta [a] anthracenes, Tetraazaindeno [5, 4‐b] fluorenes, and …
AM Abdella, AM Abdelmoniem… - Mini Reviews in …, 2020 - ingentaconnect.com
Objective: Novel bis (1, 4-dihydropyridine-3, 5-dicarbonitrile) derivatives linked to aliphatic or aromatic cores via amide or ester-amide linkages were prepared and their structures …