Heart transplantation from donation after circulatory death (DCD) donors has the potential to
substantially increase overall heart transplant activity. The aim of this report is to review the …

Cardiac transplantation has become limited by a critical shortage of suitable organs from
brain-dead donors. Reports describing the successful clinical transplantation of hearts …

BACKGROUND Donation after circulatory death (DCD) offers an additional source of
cardiac allografts, potentially allowing expansion of the donor pool, but is limited owing to …

Heart transplantation remains the preferred option for improving quality of life and survival
for patients suffering from end-stage heart failure. Unfortunately, insufficient supply of …

Previous studies indicated that Ca2+/calmodulin-dependent kinase II (CaMKII), a kinase
involved in the modulation of ryanodine receptor activity, activates Ca2+-regulated protease …

The impact of the machine perfusion of donation after circulatory death (DCD) hearts with
the novel Custodiol-N solution on diastolic and coronary microvascular dysfunction is …

Objective Mitochondrial transplantation has been shown to preserve myocardial function
and viability in adult porcine hearts donated after circulatory death (DCD). Herein, we …

Cardiac reperfusion injury is a well-established outcome following treatment of acute
myocardial infarction and other types of ischemic heart conditions. Numerous …

Tissue ischemia results in intracellular pH (pH IN) acidification, and while metabolism is a
known driver of acidic pH IN, less is known about how acidic pH IN regulates metabolism …

Background: There has been an increased interest in donation after circulatory death (DCD)
to expand donor pool for cardiac transplantation. Normothermic regional perfusion (NRP) …