In this article we review recent advances made in the pathophysiology, diagnosis, and
treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on …

Lung injury resulting from inhalation of smoke or chemical products of combustion continues
to be associated with significant morbidity and mortality. Combined with cutaneous burns …

Objective: To describe the recommendations of the Pediatric Acute Lung Injury Consensus
Conference for mechanical ventilation management of pediatric patients with acute …

Inhalation injury causes a heterogeneous cascade of insults that increase morbidity and
mortality among the burn population. Despite major advancements in burn care for the past …

Abstract Introduction The Surviving Sepsis Campaign was developed to improve outcomes
for all patients with sepsis. Despite sepsis being the primary cause of death after thermal …

There is no greater trauma than a large burn. No single injury affects more organ systems
than a severe burn injury. The subsequent supraphysiologic responses to that injury lead to …

Abstract Background Ventilator-free days (VFDs) are a composite endpoint increasingly
used as the primary outcome in critical care trials. However, because of the skewed …

BACKGROUND Acute respiratory distress syndrome (ARDS) prevalence and related
outcomes in burned military casualties from Iraq and Afghanistan have not been described …

Mortality related to severe-moderate and severe ARDS remains high. We searched the
literature to update this topic. We defined severe hypoxemic respiratory failure as Pa o 2/F io …

Background Burn inhalation injury (BII) is a major cause of burn-related mortality and
morbidity. Despite published practice guidelines, no consensus exists for the best strategies …