Cannabis, or marijuana, has potential therapeutic and medicinal properties related to
multiple compounds, particularly Δ-9-tetrahydrocannabinol and cannabidiol. Over the past …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The CB 1 and CB 2 cannabinoid receptors (CB 1 R, CB 2 R) are members of the G protein-
coupled receptor (GPCR) family that were identified over 20 years ago. CB 1 Rs and CB 2 …

The identification and cloning of the two major cannabinoid (CB1 and CB2) receptors
together with the discovery of their endogenous ligands in the late 80s and early 90s …

Synthetic cannabinoid receptor agonists (SCRAs) are an evolving class of new psychoactive
substances (NPS) with structurally diverse compounds emerging each year. Due to the rapid …

The pharmacological importance of cannabinoids has been in study for several years.
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …

The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …

A long-standing literature linking endocannabinoids (ECBs) to stress, fear, and anxiety has
led to growing interest in developing novel anxiolytics targeting the ECB system. Following …

Withdrawal from opiates, such as heroin or oral narcotics, is characterized by a host of
aversive physical and emotional symptoms. High rates of relapse and limited treatment …