[HTML][HTML] Advancements in Ocular Therapy: A Review of Emerging Drug Delivery Approaches and Pharmaceutical Technologies

BR Giri, D Jakka, MA Sandoval, VR Kulkarni, Q Bao - Pharmaceutics, 2024 - mdpi.com
Eye disorders affect a substantial portion of the global population, yet the availability of
efficacious ophthalmic drug products remains limited. This can be partly ascribed to a …

Connective tissue growth factor: Role in trabecular meshwork remodeling and intraocular pressure lowering

MDS Hassan, N Razali, AS Abu Bakar… - Experimental …, 2023 - journals.sagepub.com
Connective tissue growth factor (CTGF) is a distinct signaling molecule modulating many
physiological and pathophysiological processes. This protein is upregulated in numerous …

[HTML][HTML] Glaucoma: Novel antifibrotic therapeutics for the trabecular meshwork

M Qin, C Yu-Wai-Man - European Journal of Pharmacology, 2023 - Elsevier
Glaucoma is a chronic and progressive neurodegenerative disease characterized by the
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …

Astragaloside IV attenuates ocular hypertension in a mouse model of TGFβ2 induced primary open angle glaucoma

RB Kasetti, P Maddineni, B Kodati… - International Journal of …, 2021 - mdpi.com
Elevated intraocular pressure (IOP) is a major risk factor in developing primary open angle
glaucoma (POAG), which is the most common form of glaucoma. Transforming growth factor …

[HTML][HTML] Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma

J Wu, J Wei, H Chen, Y Dang, F Lei - Current Drug Targets, 2024 - ncbi.nlm.nih.gov
Glaucoma is the most common cause of irreversible blindness worldwide. It is characterized
by progressive optic nerve degeneration and loss of visual field. Pathological increased …

Advancements and Prospects in Nanorobotic Applications for Ophthalmic Therapy

AA Menezes Ferreira, JH da Silva Felix… - ACS Biomaterials …, 2025 - ACS Publications
This study provides a bibliometric and bibliographic review of emerging applications of
micro-and nanotechnology in treating ocular diseases, with a primary focus on glaucoma …

[HTML][HTML] Green tea—A new perspective of glaucoma prevention

K Gasiunas, S Galgauskas - International Journal of …, 2022 - ncbi.nlm.nih.gov
METHODS Totally 43 young volunteers were included in the study. The experiment was
held between noon and 2 pm Two extracts—green tea and epigallocatechin gallate (EGCG …

Anti-glaucoma medications lowered decorin and altered profibrotic proteins in human tenon's fibroblasts

S Nikhalashree, R George, B Shantha, L Vijaya… - Experimental Eye …, 2022 - Elsevier
Long term exposure to anti-glaucoma medications (AGMs) leads to an increase in
extracellular matrix (ECM) accumulation in primary glaucoma patients. This study aims to …

Future research perspective on the interfacial physics of non-invasive glaucoma testing in pathogen transmission from the eyes

D Roy, S Basu - Biointerphases, 2024 - pubs.aip.org
Non-contact tonometry (NCT) is a non-invasive ophthalmologic technique to measure
intraocular pressure (IOP) using an air puff for routine glaucoma testing. Although IOP …

[PDF][PDF] Secondary Glaucoma Following Corneal Transplantation: A Comprehensive Review of Pathophysiology and Therapeutic Approaches

G Donthula, S Daigavane, G Donthula Jr - Cureus, 2024 - cureus.com
Corneal transplantation is a critical surgical procedure aimed at restoring vision in patients
with corneal blindness or severe damage. This review focuses on secondary glaucoma, a …