Artificial intelligence applied to clinical trials: opportunities and challenges

S Askin, D Burkhalter, G Calado, S El Dakrouni - Health and technology, 2023 - Springer
Abstract Background Clinical Trials (CTs) remain the foundation of safe and effective drug
development. Given the evolving data-driven and personalized medicine approach in …

Natural language processing for smart healthcare

B Zhou, G Yang, Z Shi, S Ma - IEEE Reviews in Biomedical …, 2022 - ieeexplore.ieee.org
Smart healthcare has achieved significant progress in recent years. Emerging artificial
intelligence (AI) technologies enable various smart applications across various healthcare …

A survey on recent named entity recognition and relationship extraction techniques on clinical texts

P Bose, S Srinivasan, WC Sleeman IV, J Palta… - Applied Sciences, 2021 - mdpi.com
Significant growth in Electronic Health Records (EHR) over the last decade has provided an
abundance of clinical text that is mostly unstructured and untapped. This huge amount of …

Artificial intelligence approaches using natural language processing to advance EHR-based clinical research

Y Juhn, H Liu - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
The wide adoption of electronic health record systems in health care generates big real-
world data that open new venues to conduct clinical research. As a large amount of valuable …

How can natural language processing help model informed drug development?: a review

R Bhatnagar, S Sardar, M Beheshti, JT Podichetty - JAMIA open, 2022 - academic.oup.com
Objective To summarize applications of natural language processing (NLP) in model
informed drug development (MIDD) and identify potential areas of improvement. Materials …

Cohort selection for clinical trials: n2c2 2018 shared task track 1

A Stubbs, M Filannino, E Soysal… - Journal of the …, 2019 - academic.oup.com
Abstract Objective Track 1 of the 2018 National NLP Clinical Challenges shared tasks
focused on identifying which patients in a corpus of longitudinal medical records meet and …

Applications of natural language processing in ophthalmology: present and future

JS Chen, SL Baxter - Frontiers in Medicine, 2022 - frontiersin.org
Advances in technology, including novel ophthalmic imaging devices and adoption of the
electronic health record (EHR), have resulted in significantly increased data available for …

Trends and features of the applications of natural language processing techniques for clinical trials text analysis

X Chen, H Xie, G Cheng, LKM Poon, M Leng… - Applied Sciences, 2020 - mdpi.com
Natural language processing (NLP) is an effective tool for generating structured information
from unstructured data, the one that is commonly found in clinical trial texts. Such …

A systematic review on natural language processing systems for eligibility prescreening in clinical research

B Idnay, C Dreisbach, C Weng… - Journal of the American …, 2022 - academic.oup.com
Objective We conducted a systematic review to assess the effect of natural language
processing (NLP) systems in improving the accuracy and efficiency of eligibility …

Multilabel classification of medical concepts for patient clinical profile identification

C Gérardin, P Wajsbürt, P Vaillant, A Bellamine… - Artificial Intelligence in …, 2022 - Elsevier
Background The development of electronic health records has provided a large volume of
unstructured biomedical information. Extracting patient characteristics from these data has …