Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

MicrobiomeAnalyst is an easy-to-use, web-based platform for comprehensive analysis of
common data outputs generated from current microbiome studies. It enables researchers …

Microglial function declines during aging. The interaction of microglia with the gut microbiota
has been well characterized during development and adulthood but not in aging. Here, we …

Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …

Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Discharge of treated sewage leads to release of antibiotic resistant bacteria, resistance
genes and antibiotic residues to the environment. However, it is unclear whether increased …

The gut microbiome is increasingly implicated in modifying susceptibility to and progression
of neurodegenerative diseases (NDs). In this review, we discuss roles for the microbiome in …

Objective Chronic systemic inflammation contributes to the pathogenesis of many age‐
related diseases. Although not well understood, alterations in the gut microbiota, or …

The" holobiont" concept, defined as the collective contribution of the eukaryotic and
prokaryotic counterparts to the multicellular organism, introduces a complex definition of …