As a kind of traditional food, gluten is widely studied for its physical and chemical properties
after processing, while little attention is paid to the simulation cooking processing, digestion …

Protein tertiary structure mimetics are valuable tools to target large protein–protein
interaction interfaces. Here, we demonstrate a strategy for designing dimeric helix-hairpin …

Abundant n→ π* interactions between adjacent backbone carbonyl groups, identified by
statistical analysis of protein structures, are predicted to play an important role in dictating …

Sickle cell anemia disease has been a great challenge to the world in the present situation.
It occurs only due to the polymerization of sickle hemoglobin (HbS) having Pro–Val–Glu …

Staphylococcus aureus protein A (SpA) is an IgG Fc-binding virulence factor that is widely
used in antibody purification and as a scaffold to develop affinity molecules. A cyclized SpA …

Amino acid side chains are key to fine‐tuning the microenvironment polarity in proteins
composed of polar amide bonds. Here, we report that substituting an oxygen atom of the …

Single-point mutations are pivotal in molecular zoology, shaping functions and influencing
genetic diversity and evolution. Here we study three such genetic variants of a mechano …

Transcription factor NAM-B1 has a major role in the process of senescence, which results in
higher Fe and Zn concentrations in grains of wild wheat (T. durum; Td). The absence of the …

Abstract The bacterial toxin CcdB (Controller of Cell death or division B) targets DNA
Gyrase, an essential bacterial topoisomerase, which is also the molecular target for …

The unique physicochemical properties of a thioamide bond, which is an ideal isostere of an
amide bond, have not been fully exploited because of the tedious synthesis of thionated …