Wielding the double-edged sword: Redox drug delivery systems for inflammatory bowel disease

Y Chen, M Shui, Q Yuan, CT Vong, Z Yang… - Journal of Controlled …, 2023 - Elsevier
The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

Lipid nanovesicles for biomedical applications:'What is in a name'?

AC Apolinário, L Hauschke, JR Nunes… - Progress in lipid research, 2021 - Elsevier
Vesicles, generally defined as self-assembled structures formed by single or multiple
concentric bilayers that surround an aqueous core, have been widely used for biomedical …

Antioxidant activities of curcumin and ascorbyl dipalmitate nanoparticles and their activities after incorporation into cellulose-based packaging films

P Sonkaew, A Sane, P Suppakul - Journal of agricultural and food …, 2012 - ACS Publications
Curcumin (Ccm) and ascorbyl dipalmitate (ADP) nanoparticles (NPs) with average sizes
of∼ 50 and∼ 80 nm, respectively, were successfully produced by rapid expansion of …

Liposomal quercetin: evaluating drug delivery in vitro and biodistribution in vivo

W Gang, WJ Jie, ZL Ping, DS Ming, LJ Ying… - Expert opinion on …, 2012 - Taylor & Francis
Objective: The drug-loaded PEGylated nanomaterials have shown effective cell-killing in
vitro, but to the best of authors' knowledge there have been no reports of successful drug …

Kinetic and thermodynamic aspects of the chain-breaking antioxidant activity of ascorbic acid derivatives in non-aqueous media

R Amorati, GF Pedulli, L Valgimigli - Organic & biomolecular chemistry, 2011 - pubs.rsc.org
Ascorbic acid (vit. C) is a cofactor whose reactivity toward peroxyl and other radical species
has a key-role in its biological function. At physiological pH it is dissociated to the …

Drug nanoparticle formulation using ascorbic acid derivatives

K Moribe, W Limwikrant, K Higashi… - Journal of drug …, 2011 - Wiley Online Library
Drug nanoparticle formulation using ascorbic acid derivatives and its therapeutic uses have
recently been introduced. Hydrophilic ascorbic acid derivatives such as ascorbyl glycoside …

Characterization of nanoparticles using DSPE-PEG2000 and soluplus

R Takayama, Y Inoue, I Murata, I Kanamoto - Colloids and Interfaces, 2020 - mdpi.com
The aim of this study was to evaluate the characterized hydration method to prepare
nanoparticles using Soluplus, a block copolymer with amphipathic properties, and distearoyl …

A Theoretical Analysis of Interaction Energies and Intermolecular Interactions between Amphotericin B and Potential Bioconjugates Used in the Modification of …

J Cuellar, L Parada-Díaz, J Garza, SM Mejía - Molecules, 2023 - mdpi.com
Amphotericin B (AmB) is an antibiotic with a wide spectrum of action and low multidrug
resistance, although it exhibits self-aggregation, low specificity, and solubility in aqueous …

Improvement of extracellular lipase production by a newly isolated Yarrowia lipolytica mutant and its application in the biosynthesis of L-ascorbyl palmitate

L Ping, X Yuan, M Zhang, Y Chai, S Shan - International journal of …, 2018 - Elsevier
Yarrowia lipolytica Wt-11 producing an extracellular lipase was isolated and identified. To
improve the lipase production, Y. lipolytica Wt-11 was subjected to low-energy ion …

Understanding the rod-to-tube transformation of self-assembled ascorbyl dipalmitate lipid nanoparticles stabilized with PEGylated lipids

Z Chen, K Higashi, Y Shigehisa, K Ueda, K Yamamoto… - Nanoscale, 2023 - pubs.rsc.org
We previously established a nanoparticle-based drug delivery system (DDS) for high-dose
ascorbic acid therapy by self-assembly of a lipid-modified ascorbic acid derivative, L …