A review of keratoconus: diagnosis, pathophysiology, and genetics

VM Tur, C MacGregor, R Jayaswal, D O'Brart… - Survey of …, 2017 - Elsevier
We discuss new approaches to the early detection of keratoconus and recent investigations
regarding the nature of its pathophysiology. We review the current evidence for its complex …

Keratoconus: an inflammatory disorder?

V Galvis, T Sherwin, A Tello, J Merayo, R Barrera… - Eye, 2015 - nature.com
Keratoconus has been classically defined as a progressive, non-inflammatory condition,
which produces a thinning and steepening of the cornea. Its pathophysiological …

Keratoconus: a review

M Romero-Jiménez, J Santodomingo-Rubido… - Contact Lens and …, 2010 - Elsevier
Keratoconus is the most common primary ectasia. It usually occurs in the second decade of
life and affects both genders and all ethnicities. The estimated prevalence in the general …

The keratoconus enigma: a review with emphasis on pathogenesis

G Ferrari, P Rama - The ocular surface, 2020 - Elsevier
Purpose To review the literature on the etiopathogenesis of keratoconus (KC). Methods A
literature search was conducted using PUBMED and Google Scholar for keratoconus. The …

Eye rubbing in the aetiology of keratoconus: a systematic review and meta-analysis

S Sahebjada, HH Al-Mahrouqi, S Moshegov… - Graefe's Archive for …, 2021 - Springer
Purpose Keratoconus is a potentially blinding condition that slowly deforms the cornea in
young people. Despite the increasing prevalence of keratoconus, the exact aetiology of the …

Treatment options for advanced keratoconus: a review

JS Parker, K van Dijk, GRJ Melles - Survey of ophthalmology, 2015 - Elsevier
Traditionally, the mainstay of treatment for advanced keratoconus (KC) has been either
penetrating or deep anterior lamellar keratoplasty (PK or DALK, respectively). The success …

The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the tear film subcommittee

JP Craig, MDP Willcox, P Argüeso… - … & visual science, 2013 - iovs.arvojournals.org
The aim of the subcommittee report was to review published evidence describing tear film
changes secondary to contact lens wear and to examine the evidence for associations …

Pediatric keratoconus: a review of the literature

S Mukhtar, BK Ambati - International ophthalmology, 2018 - Springer
Purpose To describe the epidemiology and prevalence, rates of progression, difference
between adult and pediatric populations, and therapeutic approaches to pediatric …

[HTML][HTML] Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A

R Shetty, A Ghosh, RR Lim… - … & visual science, 2015 - tvst.arvojournals.org
Purpose.: The present study was designed to understand the role of inflammatory cytokines
secreted by corneal epithelial cells in keratoconus (KC) and the response to treatment with …

Molecular and histopathological changes associated with keratoconus

ML Khaled, I Helwa, M Drewry… - BioMed research …, 2017 - Wiley Online Library
Keratoconus (KC) is a corneal thinning disorder that leads to loss of visual acuity through
ectasia, opacity, and irregular astigmatism. It is one of the leading indicators for corneal …