A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

Matrix metalloproteinases (MMPs) are the major protease family responsible for the
cleavage of the matrisome (global composition of the extracellular matrix (ECM) proteome) …

Silicate bioceramics have been considered to possess a wide prospect of clinical
application for orthopedic tissue regeneration due to their excellent osteogenesis and …

Bone-forming cells originate from distinct embryological layers, mesoderm (axial and
appendicular bones) and ectoderm (precursor of neural crest cells, which mainly form facial …

Bone development and healing processes involve a complex cascade of biological events
requiring well-orchestrated synergism with bone cells, growth factors, and other trophic …

Background: Embryonic development can often adjust its morphogenetic processes to
counteract external perturbation. The existence of self‐monitoring responses during pattern …

Scaffold materials should favor cell attachment and proliferation, and provide designable 3D
structures with appropriate mechanical strength. Collagen matrices have proven to be …

Background The cell-material interaction is a complex bi-directional and dynamic process
that mimics to a certain extent the natural interactions of cells with the extracellular matrix …

Since Branemark's findings, titanium-based alloys have been widely used in implantology.
However, their success in dental implants is not known when considering the heterogenicity …

It is important to understand the cellular and molecular events that occur at the cell–material
interface of implants used for bone repair. The mechanisms involved in the initial stages of …