Skin cancer is the most commonly diagnosed cancer worldwide. Understanding the natural
history of skin cancer provides the framework for the creation of prevention and control …

Five years ago, the Melanoma Research Foundation (MRF) conducted an assessment of the
challenges and opportunities facing the melanoma research community and patients with …

The impact of protein therapeutics in healthcare is steadily increasing, due to advancements
in the field of biotechnology and a deeper understanding of several pathologies. However …

Background Many drugs approved for other indications can control the growth of tumor cells
and limit adverse events (AE). Data sources Literature searches with keywords 'repurposing …

Signal transducer and activator of transcription 3 (STAT3) has been proposed as a target for
melanoma prevention. Luteolin, a bioactive flavonoid abundant in medicinal herbs, has …

Incorporation of bioactive natural compounds like polyphenols is an attractive approach for
enhanced functionalities of biomaterials. In particular flavonoids have important …

Simple Summary Melanocytes are the pigment-producing cells in the skin that help to
protect it against damaging solar ultraviolet radiation. As they engage in this function, they …

Simple Summary Melanoma is a deadly skin cancer, and the incidence of melanoma is
rising. Chemoprevention, using small molecule drugs to prevent the development of cancer …

Simple Summary Melanoma constitutes a major public health risk, with the rates of
diagnosis increasing on a yearly basis. Monitoring for risk factors and preventing dangerous …

Proteins play a vital role in diverse biological processes in the human body, and protein
therapeutics have been applied to treat different diseases such as cancers, genetic …