Diabetes mellitus (DM) is one of the most prevalent chronic diseases worldwide. High
morbidity and mortality caused by DM are closely linked to its complications in multiple …

The scientific interest in irisin, a myokine discovered in 2012, has grown exponentially in
recent years. Irisin, which is mainly produced in skeletal muscle, influences the browning …

Skeletal muscle plays a major role in controlling body mass and metabolism: it is the most
abundant tissue of the body and a major source of humoral factors; in addition, it is primarily …

Skeletal muscle plays a crucial role in motor function, respiration, and whole-body energy
homeostasis. How to regulate the development and function of skeletal muscle has become …

Adipose tissue (AT) can be classified into two different types:(i) white adipose tissue (WAT),
which represents the largest amount of total AT, and has the main function of storing fatty …

Simple Summary Regarding the pandemic of obesity and chronic diseases associated to
metabolic alterations that occur nowadays worldwide, here, we review the most recent …

Objective To examine the expression and regulation of fibronectin type III domain-containing
protein 5/irisin (FNDC5/irisin) in primary human periodontal ligament (hPDL) cells, dental …

Irisin is a hormone-like myokine produced in abundance by skeletal muscle (SkM) in
response to exercise. This myokine, identical in humans and mice, is involved in many …

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Sclerostin is a protein secreted by osteocytes whose encoding gene SOST is regulated by
mechanical stimuli, cytokines, and all-trans retinoic acid (ATRA) and mediates antianabolic …