Abstract Chicago Classification v4. 0 (CCv4. 0) is the updated classification scheme for
esophageal motility disorders using metrics from high‐resolution manometry (HRM). Fifty …

Clinical history, questionnaire data and response to antisecretory therapy are insufficient to
make a conclusive diagnosis of GERD in isolation, but are of value in determining need for …

Gastroesophageal reflux disease (GERD) is a common clinical disease associated with
upper gastrointestinal motility disorders. Recently, with improvements in living standards …

Erosive esophagitis (EE) is the part of gastroesophageal reflux disease (GERD) spectrum
and may progress to esophageal adenocarcinoma. Due to its progressivity and unclear …

Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in
the general population has recently increased. GERD is a chronic relapsing disease …

Esophagogastric junction (EGJ) barrier function is of fundamental importance in the
pathophysiology of gastroesophageal reflux disease. Impaired EGJ barrier function leads to …

Gastroesophageal reflux disease (GERD), a prevalent clinical condition, is often attributed to
aberrant esophageal motility, leading to gastric content reflux and associated symptoms or …

Heartburn is a common symptom in clinical practice, but as many as 70% of patients have
normal findings from upper endoscopy. Most of these patients have nonerosive reflux …

Background Esophagogastric junction contractile integral (EGJ‐CI) and EGJ morphology
are high‐resolution manometry (HRM) metrics that assess EGJ barrier function. Normative …

Lower esophageal sphincter (LES) pathophysiology has been established in
gastroesophageal reflux disease (GERD); however, less is understood regarding the role …