[HTML][HTML] Hepatic ischemia and reperfusion injury: effects on the liver sinusoidal milieu

C Peralta, MB Jiménez-Castro, J Gracia-Sancho - Journal of hepatology, 2013 - Elsevier
Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

[HTML][HTML] Cellular and molecular mechanisms of hepatic ischemia-reperfusion injury: The role of oxidative stress and therapeutic approaches

J George, Y Lu, M Tsuchishima, M Tsutsumi - Redox biology, 2024 - Elsevier
Ischemia-reperfusion (IR) or reoxygenation injury is the paradoxical exacerbation of cellular
impairment following restoration of blood flow after a period of ischemia during surgical …

Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by the …

JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate rat hepatic ischemia‐reperfusion injury by suppressing oxidative stress …

J Yao, J Zheng, J Cai, K Zeng, C Zhou… - The FASEB …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been reported to exert therapeutic effects on
immunoregulation, tissue repair, and regeneration from the bench to the bedside. Increasing …

Adipose mesenchymal stem cell–derived exosomal microRNAs ameliorate polycystic ovary syndrome by protecting against metabolic disturbances

M Cao, Y Zhao, T Chen, Z Zhao, B Zhang, C Yuan… - Biomaterials, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in
women of childbearing age. Adipose mesenchymal stem cells (AMSCs) secrete cytokines …

[HTML][HTML] Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: What does the future have in store for us?

B Lascaris, VE de Meijer, RJ Porte - Journal of Hepatology, 2022 - Elsevier
Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

Hepatoprotective effect of exosomes from human-induced pluripotent stem cell–derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats

K Nong, W Wang, X Niu, B Hu, C Ma, Y Bai, B Wu… - Cytotherapy, 2016 - Elsevier
Background This study aimed to evaluate the effect of exosomes produced by human-
induced pluripotent stem cell–derived mesenchymal stromal cells (hiPSC-MSCs-Exo) on …

MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation

J Zheng, L Chen, T Lu, Y Zhang, X Sui, Y Li… - Cell death & …, 2020 - nature.com
Hepatocyte apoptosis is the main pathophysiological process underlying liver
ischemia/reperfusion (I/R) injury. Mitochondrial abnormalities have a vital role in …

[PDF][PDF] Extracellular vesicles from bone marrow–derived mesenchymal stem cells protect against murine hepatic ischemia/reperfusion injury

H Haga, IK Yan, DA Borrelli, A Matsuda… - Liver …, 2017 - Wiley Online Library
Hepatic ischemia/reperfusion injury (IRI) and associated inflammation contributes to liver
dysfunction and complications after liver surgery and transplantation. Mesenchymal stem …

Cell-based therapy for acute organ injury: preclinical evidence and on-going clinical trials using mesenchymal stem cells

A Monsel, Y Zhu, S Gennai, Q Hao, J Liu… - …, 2014 - pmc.ncbi.nlm.nih.gov
Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver or
brain. Genomic, proteomic and metabolomic approaches highlight common injury …